 Echinocandins
"Echinocandins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
| Descriptor ID |
D054714
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| MeSH Number(s) |
D12.644.641.311
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Echinocandins".
Below are MeSH descriptors whose meaning is more specific than "Echinocandins".
This graph shows the total number of publications written about "Echinocandins" by people in this website by year, and whether "Echinocandins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Echinocandins" by people in Profiles.
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Pande A, Non LR, Romee R, Santos CA. Pseudozyma and other non-Candida opportunistic yeast bloodstream infections in a large stem cell transplant center. Transpl Infect Dis. 2017 Apr; 19(2).
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Cross DM, Chmielewski G, Lewis EM, Liu L, Modesitt MS, Ripp SL, Sawaryn CM, Bowman CJ. Non-clinical safety assessment and toxicokinetics of voriconazole and anidulafungin in the juvenile rat: a combination study design in support of a Paediatric Investigation Plan. Regul Toxicol Pharmacol. 2012 Jun; 63(1):29-39.
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Ripp SL, Aram JA, Bowman CJ, Chmielewski G, Conte U, Cross DM, Gao H, Lewis EM, Lin J, Liu P, Schlamm HT. Tissue distribution of anidulafungin in neonatal rats. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb; 95(1):89-94.
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Bowman CJ, Chmielewski G, Lewis E, Ripp S, Sawaryn CM, Cross DM. Juvenile toxicity assessment of anidulafungin in rats: an example of navigating case-by-case study design through scientific and regulatory challenges. Birth Defects Res B Dev Reprod Toxicol. 2011 Aug; 92(4):333-44.
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Forrest GN, Rasetto F, Akpek G, Philosophe B. Safety and efficacy of micafungin in transplantation recipients. Transplantation. 2006 Dec 15; 82(11):1549.
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Odds FC, Motyl M, Andrade R, Bille J, Cantón E, Cuenca-Estrella M, Davidson A, Durussel C, Ellis D, Foraker E, Fothergill AW, Ghannoum MA, Giacobbe RA, Gobernado M, Handke R, Laverdière M, Lee-Yang W, Merz WG, Ostrosky-Zeichner L, Pemán J, Perea S, Perfect JR, Pfaller MA, Proia L, Rex JH, Rinaldi MG, Rodriguez-Tudela JL, Schell WA, Shields C, Sutton DA, Verweij PE, Warnock DW. Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species. J Clin Microbiol. 2004 Aug; 42(8):3475-82.
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Madariaga MG, Tenorio A, Proia L. Trichosporon inkin peritonitis treated with caspofungin. J Clin Microbiol. 2003 Dec; 41(12):5827-9.
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