"Lectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
| Descriptor ID |
D037102
|
| MeSH Number(s) |
D12.776.503
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lectins".
Below are MeSH descriptors whose meaning is more specific than "Lectins".
This graph shows the total number of publications written about "Lectins" by people in this website by year, and whether "Lectins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lectins" by people in Profiles.
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Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells. Front Immunol. 2018; 9:2138.
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A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus. J Biol Chem. 2010 Aug 06; 285(32):24729-39.
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L-ficolin binding and lectin pathway activation by acetylated low-density lipoprotein. Clin Exp Immunol. 2008 Feb; 151(2):275-83.
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Interaction of human immunodeficiency virus (HIV) glycans with lectins of the human immune system. Curr Protein Pept Sci. 2006 Aug; 7(4):317-24.
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Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol. 2005 Aug; 116(2):305-11.
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Interaction of mannose-binding lectin with primary isolates of human immunodeficiency virus type 1. J Gen Virol. 2000 Apr; 81(Pt 4):949-55.
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Changes in messenger RNA and protein levels of proteoglycans and link protein in human osteoarthritic cartilage samples. Arthritis Rheum. 1997 Jun; 40(6):1037-45.
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Induction of reversible changes in cell-surface glycoconjugates and lung colonization potential by 13-cis retinoic acid. J Cell Biochem. 1988 Jun; 37(2):213-23.
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Neuroleukin: a lymphokine product of lectin-stimulated T cells. Science. 1986 Oct 31; 234(4776):574-81.