 Caveolae
"Caveolae" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endocytic/exocytic CELL MEMBRANE STRUCTURES rich in glycosphingolipids, cholesterol, and lipid-anchored membrane proteins that function in ENDOCYTOSIS (potocytosis), transcytosis, and SIGNAL TRANSDUCTION. Caveolae assume various shapes from open pits to closed vesicles. Caveolar coats are composed of CAVEOLINS.
| Descriptor ID |
D021941
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| MeSH Number(s) |
A11.284.149.165.175.160 A11.284.149.165.570.160 A11.284.430.214.190.875.190.880.180.160
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caveolae".
Below are MeSH descriptors whose meaning is more specific than "Caveolae".
This graph shows the total number of publications written about "Caveolae" by people in this website by year, and whether "Caveolae" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 2 | 3 | | 2005 | 1 | 1 | 2 | | 2007 | 0 | 2 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caveolae" by people in Profiles.
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Bardita C, Predescu DN, Sha F, Patel M, Balaji G, Predescu SA. Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5. J Cell Sci. 2015 Apr 15; 128(8):1528-41.
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Knezevic I, Predescu D, Bardita C, Wang M, Sharma T, Keith B, Neamu R, Malik AB, Predescu S. Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s. J Cell Mol Med. 2011 Nov; 15(11):2364-76.
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Nag S, Kapadia A, Stewart DJ. Review: molecular pathogenesis of blood-brain barrier breakdown in acute brain injury. Neuropathol Appl Neurobiol. 2011 Feb; 37(1):3-23.
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Klein IK, Predescu DN, Sharma T, Knezevic I, Malik AB, Predescu S. Intersectin-2L regulates caveola endocytosis secondary to Cdc42-mediated actin polymerization. J Biol Chem. 2009 Sep 18; 284(38):25953-61.
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Nag S, Venugopalan R, Stewart DJ. Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown. Acta Neuropathol. 2007 Nov; 114(5):459-69.
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Predescu SA, Predescu DN, Malik AB. Molecular determinants of endothelial transcytosis and their role in endothelial permeability. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L823-42.
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Miyawaki-Shimizu K, Predescu D, Shimizu J, Broman M, Predescu S, Malik AB. siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L405-13.
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Predescu SA, Predescu DN, Shimizu K, Klein IK, Malik AB. Cholesterol-dependent syntaxin-4 and SNAP-23 clustering regulates caveolar fusion with the endothelial plasma membrane. J Biol Chem. 2005 Nov 04; 280(44):37130-8.
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Dedkova EN, Ji X, Lipsius SL, Blatter LA. Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C406-15.
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Predescu SA, Predescu DN, Timblin BK, Stan RV, Malik AB. Intersectin regulates fission and internalization of caveolae in endothelial cells. Mol Biol Cell. 2003 Dec; 14(12):4997-5010.
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