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Erik Schadde

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentSurgery
Address
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    My Scopus ID is 6602382773.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Williams MD, Fei M, Schadde E, Hollinger EF, Chan EY, Olaitan O. Early Experience Using Donor-derived Cell-free DNA for Surveillance of Rejection Following Simultaneous Pancreas and Kidney Transplantation. Transplant Direct. 2022 May; 8(5):e1321. PMID: 35415217.
      View in: PubMed
    2. Williams MD, Thomas J, Paner A, Chan EY, Hollinger EF, Schadde E, Hertl M, Santos CAQ, Olaitan OK. Can Donor-Derived Cell-Free DNA Detect Graft-Versus-Host Disease in Solid Organ Transplantation: A Case Report. Transplant Proc. 2022 Jan-Feb; 54(1):176-179. PMID: 34961600.
      View in: PubMed
    3. Heid F, Toti J, C Balzarotti Canger R, Cristaudi A, Breitenstein S, Majno-Hurst P, Schadde E. Is laparoscopic major hepatectomy feasible and safe in Swiss cantonal hospitals? Swiss Med Wkly. 2021 12 20; 151:w30044. PMID: 34964580.
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    4. Heil J, Heid F, Bechstein WO, Björnsson B, Brismar TB, Carling U, Erdmann J, Fretland ÅA, Grunhagen D, Hana RA, Hohmann J, Linke R, Meyer Y, Nawawi A, Olthof PB, Sandström P, Schnitzbauer AA, Sparrelid E, Verhoef C, Metrakos P, Schadde E. Sarcopenia predicts reduced liver growth and reduced resectability in patients undergoing portal vein embolization before liver resection - A DRAGON collaborative analysis of 306 patients. HPB (Oxford). 2022 03; 24(3):413-421. PMID: 34526229.
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    5. Stavrou GA, Stang A, Raptis DA, Schadde E, Zeile M, Brüning R, Wagner KC, Huber TM, Oldhafer KJ. Intraoperative (Contrast-Enhanced) Ultrasound Has the Highest Diagnostic Accuracy of Any Imaging Modality in Resection of Colorectal Liver Metastases. J Gastrointest Surg. 2021 12; 25(12):3160-3169. PMID: 34159555.
      View in: PubMed
    6. Lalazar G, Requena D, Ramos-Espiritu L, Ng D, Bhola PD, de Jong YP, Wang R, Narayan NJC, Shebl B, Levin S, Michailidis E, Kabbani M, Vercauteren KOA, Hurley AM, Farber BA, Hammond WJ, Saltsman JA, Weinberg EM, Glickman JF, Lyons BA, Ellison J, Schadde E, Hertl M, Leiting JL, Truty MJ, Smoot RL, Tierney F, Kato T, Wendel HG, LaQuaglia MP, Rice CM, Letai A, Coffino P, Torbenson MS, Ortiz MV, Simon SM. Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening. Cancer Discov. 2021 10; 11(10):2544-2563. PMID: 34127480.
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    7. Santos CAQ, Rhee Y, Hollinger EF, Olaitan OK, Schadde E, Peev V, Saltzberg SN, Hertl M. Comparative incidence and outcomes of COVID-19 in kidney or kidney-pancreas transplant recipients versus kidney or kidney-pancreas waitlisted patients: A single-center study. Clin Transplant. 2021 08; 35(8):e14362. PMID: 33998716.
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    8. Najafi A, Schadde E, Binkert CA. Combined simultaneous embolization of the portal vein and hepatic vein (double vein embolization) - a technical note about embolization sequence. CVIR Endovasc. 2021 May 26; 4(1):43. PMID: 34037882.
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    9. Schadde E, Grunhagen DJ, Verhoef C, Krzywon L, Metrakos P. Limitations in resectability of colorectal liver metastases 2020 - A systematic approach for clinicians and patients. Semin Cancer Biol. 2021 06; 71:10-20. PMID: 32980499.
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    10. Heil J, Schadde E. Simultaneous portal and hepatic vein embolization before major liver resection. Langenbecks Arch Surg. 2021 Aug; 406(5):1295-1305. PMID: 32839889.
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    11. Madoff DC, Odisio BC, Schadde E, Gaba RC, Bennink RJ, van Gulik TM, Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Curr Oncol Rep. 2020 05 16; 22(6):59. PMID: 32415401.
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    12. Dirscherl K, Schläpfer M, Roth Z'graggen B, Wenger RH, Booy C, Flury-Frei R, Fatzer R, Aloman C, Bartosch B, Parent R, Kurtcuoglu V, de Zélicourt D, Spahn DR, Beck Schimmer B, Schadde E. Hypoxia sensing by hepatic stellate cells leads to VEGF-dependent angiogenesis and may contribute to accelerated liver regeneration. Sci Rep. 2020 03 09; 10(1):4392. PMID: 32152325.
      View in: PubMed
    13. Schadde E. Combined portal vein and hepatic vein embolization-finally the platinum procedure of regenerative liver surgery? Hepatobiliary Surg Nutr. 2020 Feb; 9(1):92-94. PMID: 32140488.
      View in: PubMed
    14. Tierney JF, Chivukula SV, Poirier J, Pappas SG, Schadde E, Hertl M, Kebebew E, Keutgen X. National Treatment Practice for Adrenocortical Carcinoma: Have They Changed and Have We Made Any Progress? J Clin Endocrinol Metab. 2019 12 01; 104(12):5948-5956. PMID: 31361313.
      View in: PubMed
    15. Olthof PB, van Dam R, Jovine E, Campos RR, de Santibañes E, Oldhafer K, Malago M, Abdalla EK, Schadde E. Accuracy of estimated total liver volume formulas before liver resection. Surgery. 2019 09; 166(3):247-253. PMID: 31204072.
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    16. Tierney JF, Poirier J, Chivukula S, Pappas SG, Hertl M, Schadde E, Keutgen X. Primary Tumor Site Affects Survival in Patients with Gastroenteropancreatic and Neuroendocrine Liver Metastases. Int J Endocrinol. 2019; 2019:9871319. PMID: 30992703.
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    17. Kalil JA, Poirier J, Becker B, Van Dam R, Keutgen X, Schadde E. Laparoscopic Parenchymal-Sparing Hepatectomy: the New Maximally Minimal Invasive Surgery of the Liver-a Systematic Review and Meta-Analysis. J Gastrointest Surg. 2019 04; 23(4):860-869. PMID: 30756316.
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    18. Skertich NJ, Gerard J, Poirier J, Hertl M, Pappas SG, Schadde E, Keutgen XM. Do All Abdominal Neuroendocrine Tumors Require Extended Postoperative VTE Prophylaxis? A NSQIP Analysis. J Gastrointest Surg. 2019 04; 23(4):788-793. PMID: 30671795.
      View in: PubMed
    19. Huiskens J, Schadde E, Lang H, Malago M, Petrowsky H, de Santibañes E, Oldhafer K, van Gulik TM, Olthof PB. Avoiding postoperative mortality after ALPPS-development of a tumor-specific risk score for colorectal liver metastases. HPB (Oxford). 2019 07; 21(7):898-905. PMID: 30611560.
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    20. Schürner AM, Manzini G, Bueter M, Schadde E, Beck-Schimmer B, Schläpfer M. Perioperative surgery- and anaesthesia-related risks of laparoscopic Roux-en-Y gastric bypass - a single centre, retrospective data analysis. BMC Anesthesiol. 2018 12 13; 18(1):190. PMID: 30545308.
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    21. Tierney JF, Kosche C, Schadde E, Ali A, Virmani S, Pappas SG, Poirier J, Keutgen XM. 68Gallium-DOTATATE positron emission tomography-computed tomography (PET CT) changes management in a majority of patients with neuroendocrine tumors. Surgery. 2019 01; 165(1):178-185. PMID: 30415869.
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    22. Schadde E, Guiu B, Deal R, Kalil J, Arslan B, Tasse J, Olthof PB, Heil J, Schnitzbauer AA, Jakate S, Breitenstein S, Schläpfer M, Beck Schimmer B, Hertl M. Simultaneous hepatic and portal vein ligation induces rapid liver hypertrophy: A study in pigs. Surgery. 2019 03; 165(3):525-533. PMID: 30482517.
      View in: PubMed
    23. Tierney JF, Chivukula SV, Wang X, Pappas SG, Schadde E, Hertl M, Poirier J, Keutgen XM. Resection of primary tumor may prolong survival in metastatic gastroenteropancreatic neuroendocrine tumors. Surgery. 2019 03; 165(3):644-651. PMID: 30366604.
      View in: PubMed
    24. Keutgen XM, Schadde E, Pommier RF, Halfdanarson TR, Howe JR, Kebebew E. Metastatic neuroendocrine tumors of the gastrointestinal tract and pancreas: A surgeon's plea to centering attention on the liver. Semin Oncol. 2018 08; 45(4):232-235. PMID: 30318110.
      View in: PubMed
    25. Beck-Schimmer B, Roth Z'graggen B, Booy C, Köppel S, Spahn DR, Schläpfer M, Schadde E. Sevoflurane Protects Hepatocytes From Ischemic Injury by Reducing Reactive Oxygen Species Signaling of Hepatic Stellate Cells: Translational Findings Based on a Clinical Trial. Anesth Analg. 2018 10; 127(4):1058-1065. PMID: 30216289.
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    26. Olthof PB, Schnitzbauer AA, Schadde E. The HPB controversy of the decade: 2007-2017 - Ten years of ALPPS. Eur J Surg Oncol. 2018 10; 44(10):1624-1627. PMID: 29954639.
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    27. Schnitzbauer AA, Schadde E, Linecker M, Machado MA, Adam R, Malago M, Clavien PA, de Santibanes E, Bechstein WO. Indicating ALPPS for Colorectal Liver Metastases: A Critical Analysis of Patients in the International ALPPS Registry. Surgery. 2018 09; 164(3):387-394. PMID: 29803563.
      View in: PubMed
    28. Breitenstein S, Zehnder A, Gelpke H, Soll C, Adamina M, Grieder F, Schadde E, Grochola LF. [Colorectal metastases - Current treatment strategies]. Ther Umsch. 2018; 75(10):634-641. PMID: 31232665.
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    29. Lang H, Mittler J, Oldhafer KJ, Schadde E, Yamamoto Y. Frontiers of Liver Surgery. Visc Med. 2017 Dec; 33(6):463-465. PMID: 29344521.
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    30. Kang D, Schadde E. Hypertrophy and Liver Function in ALPPS: Correlation with Morbidity and Mortality. Visc Med. 2017 Dec; 33(6):426-433. PMID: 29344516.
      View in: PubMed
    31. Labgaa I, Slankamenac K, Schadde E, Jibara G, Alshebeeb K, Mentha G, Clavien PA, Schwartz M. Liver resection for metastases not of colorectal, neuroendocrine, sarcomatous, or ovarian (NCNSO) origin: A multicentric study. Am J Surg. 2018 Jan; 215(1):125-130. PMID: 29061283.
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    32. Enne M, Schadde E, Björnsson B, Hernandez Alejandro R, Steinbruck K, Viana E, Robles Campos R, Malago M, Clavien PA, De Santibanes E, Gayet B. ALPPS as a salvage procedure after insufficient future liver remnant hypertrophy following portal vein occlusion. HPB (Oxford). 2017 12; 19(12):1126-1129. PMID: 28917644.
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    33. Schadde E, Hertl M, Breitenstein S, Beck-Schimmer B, Schläpfer M. Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure. J Vis Exp. 2017 08 14; (126). PMID: 28829432.
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    34. Deshayes E, Schadde E, Piron L, Quenet F, Guiu B. Extended Liver Venous Deprivation Leads to a Higher Increase in Liver Function that ALPPS in Early Assessment : A comment to "Sparrelid, E. et al. Dynamic Evaluation of Liver Volume and Function in Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy. Journal of Gastrointestinal Surgery (2017)". J Gastrointest Surg. 2017 10; 21(10):1754-1755. PMID: 28785933.
      View in: PubMed
    35. Deal R, Frederiks C, Williams L, Olthof PB, Dirscherl K, Keutgen X, Chan E, Deziel D, Hertl M, Schadde E. Rapid Liver Hypertrophy After Portal Vein Occlusion Correlates with the Degree of Collateralization Between Lobes-a Study in Pigs. J Gastrointest Surg. 2018 02; 22(2):203-213. PMID: 28766271.
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    36. Olthof PB, Tomassini F, Huespe PE, Truant S, Pruvot FR, Troisi RI, Castro C, Schadde E, Axelsson R, Sparrelid E, Bennink RJ, Adam R, van Gulik TM, de Santibanes E. Hepatobiliary scintigraphy to evaluate liver function in associating liver partition and portal vein ligation for staged hepatectomy: Liver volume overestimates liver function. Surgery. 2017 10; 162(4):775-783. PMID: 28732555.
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    37. Eshmuminov D, Tschuor C, Raptis DA, Boss A, Wurnig MC, Sergeant G, Schadde E, Clavien PA. Rapid liver volume increase induced by associating liver partition with portal vein ligation for staged hepatectomy (ALPPS): Is it edema, steatosis, or true proliferation? Surgery. 2017 06; 161(6):1549-1552. PMID: 28410744.
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    38. Olthof PB, Schadde E, van Lienden KP, Heger M, de Bruin K, Verheij J, Bennink RJ, van Gulik TM. Hepatic parenchymal transection increases liver volume but not function after portal vein embolization in rabbits. Surgery. 2017 10; 162(4):732-741. PMID: 28173999.
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    39. Schadde E, Breitenstein S, Hertl M, Spahn DR, Schläpfer M, Beck-Schimmer B. Reply to: Liver hypoxia as a trigger to liver regeneration: No more than another piece of the puzzle. Surgery. 2017 04; 161(4):1177-1178. PMID: 28109617.
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    40. Machado MA, Makdissi FF, Surjan RC, Basseres T, Schadde E. Transition from open to laparoscopic ALPPS for patients with very small FLR: the initial experience. HPB (Oxford). 2017 01; 19(1):59-66. PMID: 27816312.
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    41. Olthof PB, Schadde E. The rush to novelty and high expectations in surgery: the case of ALPPS. J Clin Transl Res. 2016 Nov 10; 2(3):79-83. PMID: 30873465.
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    42. Schadde E, Tsatsaris C, Swiderska-Syn M, Breitenstein S, Urner M, Schimmer R, Booy C, Z'graggen BR, Wenger RH, Spahn DR, Hertl M, Knechtle S, Diehl AM, Schläpfer M, Beck-Schimmer B. Hypoxia of the growing liver accelerates regeneration. Surgery. 2017 03; 161(3):666-679. PMID: 27436690.
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    43. Surjan RC, Makdissi FF, Basseres T, Leite D, Charles LF, Bezerra RO, Schadde E, Machado MA. First totally laparoscopic ALPPS procedure with selective hepatic artery clamping: Case report of a new technique. Medicine (Baltimore). 2016 Jul; 95(29):e4236. PMID: 27442648.
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    44. Serenari M, Zanello M, Schadde E, Toschi E, Ratti F, Gringeri E, Masetti M, Cillo U, Aldrighetti L, Jovine E. Importance of primary indication and liver function between stages: results of a multicenter Italian audit of ALPPS 2012-2014. HPB (Oxford). 2016 05; 18(5):419-27. PMID: 27154805.
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    45. Buac S, Schadde E, Schnitzbauer AA, Vogt K, Hernandez-Alejandro R. The many faces of ALPPS: surgical indications and techniques among surgeons collaborating in the international registry. HPB (Oxford). 2016 05; 18(5):442-8. PMID: 27154808.
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    46. Machado MA, Surjan RC, Basseres T, Schadde E, Costa FP, Makdissi FF. The laparoscopic Glissonian approach is safe and efficient when compared with standard laparoscopic liver resection: Results of an observational study over 7 years. Surgery. 2016 09; 160(3):643-51. PMID: 26948499.
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    47. Belghiti J, Dokmak S, Schadde E. ALPPS: Innovation for innovation's sake. Surgery. 2016 May; 159(5):1287-8. PMID: 26922366.
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    48. Schadde E, Raptis DA, Schnitzbauer AA, Ardiles V, Tschuor C, Lesurtel M, Abdalla EK, Hernandez-Alejandro R, Jovine E, Machado M, Malago M, Robles-Campos R, Petrowsky H, Santibanes ED, Clavien PA. Prediction of Mortality After ALPPS Stage-1: An Analysis of 320 Patients From the International ALPPS Registry. Ann Surg. 2015 Nov; 262(5):780-5; discussion 785-6. PMID: 26583666.
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    49. Beck-Schimmer B, Bonvini JM, Schadde E, Dutkowski P, Oberkofler CE, Lesurtel M, DeOliveira ML, Figueira ER, Rocha Filho JA, Auler JO, D'Albuquerque LA, Reyntjens K, Wouters P, Rogiers X, Debaerdemaeker L, Ganter MT, Weber A, Puhan MA, Clavien PA, Breitenstein S. Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial. Transplantation. 2015 Aug; 99(8):1606-12. PMID: 25769076.
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    50. Schadde E, Hernandez-Alejandro R, Lang H, de Santibanes E, Clavien PA. ALPPS Offers a Better Chance of Complete Resection in Patients with Primarily Unresectable Liver Tumors. Results of a Multicentre Analysis: Reply. World J Surg. 2015 Jul; 39(7):1850-1. PMID: 25743483.
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    51. Schadde E, Malagó M, Hernandez-Alejandro R, Li J, Abdalla E, Ardiles V, Lurje G, Vyas S, Machado MA, de Santibañes E. Monosegment ALPPS hepatectomy: extending resectability by rapid hypertrophy. Surgery. 2015 Apr; 157(4):676-89. PMID: 25712199.
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    52. Schadde E, Clavien PA. Reply to letter: "accelerated liver hypertrophy: ALPPS and more!". Ann Surg. 2015 Feb; 261(2):e46-7. PMID: 24646541.
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    53. Ratti F, Schadde E, Masetti M, Massani M, Zanello M, Serenari M, Cipriani F, Bonariol L, Bassi N, Aldrighetti L, Jovine E. Strategies to Increase the Resectability of Patients with Colorectal Liver Metastases: A Multi-center Case-Match Analysis of ALPPS and Conventional Two-Stage Hepatectomy. Ann Surg Oncol. 2015; 22(6):1933-42. PMID: 25564160.
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    54. Schadde E, Schnitzbauer AA, Tschuor C, Raptis DA, Bechstein WO, Clavien PA. Systematic review and meta-analysis of feasibility, safety, and efficacy of a novel procedure: associating liver partition and portal vein ligation for staged hepatectomy. Ann Surg Oncol. 2015 Sep; 22(9):3109-20. PMID: 25448799.
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    55. Schadde E, Ardiles V, Robles-Campos R, Malago M, Machado M, Hernandez-Alejandro R, Soubrane O, Schnitzbauer AA, Raptis D, Tschuor C, Petrowsky H, De Santibanes E, Clavien PA. Early survival and safety of ALPPS: first report of the International ALPPS Registry. Ann Surg. 2014 Nov; 260(5):829-36; discussion 836-8. PMID: 25379854.
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    56. Ardiles V, Schadde E, Santibanes E, Clavien PA. Commentary on "Happy marriage or "dangerous liaison": ALPPS and the anterior approach". Ann Surg. 2014 Aug; 260(2):e4. PMID: 25350653.
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    57. Schadde E, Ardiles V, Slankamenac K, Tschuor C, Sergeant G, Amacker N, Baumgart J, Croome K, Hernandez-Alejandro R, Lang H, de Santibanes E, Clavien PA. ALPPS offers a better chance of complete resection in patients with primarily unresectable liver tumors compared with conventional-staged hepatectomies: results of a multicenter analysis. World J Surg. 2014 Jun; 38(6):1510-9. PMID: 24748319.
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    58. Sergeant G, Schadde E, Maleux G, Aerts R. Hepatic Artery Embolization prior to En Bloc Resection of an Encased Common Hepatic Artery in Adenocarcinoma of the Head of the Pancreas. Case Rep Med. 2013; 2013:205475. PMID: 23983701.
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    59. Künzle S, Glenck M, Puippe G, Schadde E, Mayer D, Pfammatter T. Stent-graft repairs of visceral and renal artery aneurysms are effective and result in long-term patency. J Vasc Interv Radiol. 2013 Jul; 24(7):989-96. PMID: 23727420.
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    60. Schadde E, Slankamenac K, Breitenstein S, Lesurtel M, De Oliveira M, Beck-Schimmer B, Dutkowski P, Clavien PA. Are two-stage hepatectomies associated with more complications than one-stage procedures? HPB (Oxford). 2013 Jun; 15(6):411-7. PMID: 23458579.
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    61. Waldner M, Bächler T, Schadde E, Schiesser M, Immer F, Clavien PA, Brockmann JG. New surgical technique for pediatric en-bloc kidney and pancreas transplantation: the pancreas piggy-back. Transpl Int. 2013 Jan; 26(1):30-3. PMID: 23072376.
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    62. Geier A, Schadde E, Müllhaupt B. [Current therapeutic strategies for hepatocellular carcinoma]. MMW Fortschr Med. 2012 Jul 26; 154(13):63-7; quiz 68-9. PMID: 22957387.
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    63. Dutkowski P, Oberkofler CE, Slankamenac K, Puhan MA, Schadde E, Müllhaupt B, Geier A, Clavien PA. Are there better guidelines for allocation in liver transplantation? A novel score targeting justice and utility in the model for end-stage liver disease era. Ann Surg. 2011 Nov; 254(5):745-53; discussion 753. PMID: 22042468.
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    64. Bryan CF, Luger AM, Smith JL, Warady BA, Wakefield M, Schadde E, Murillo D, Nelson PW. Sharing kidneys across donor-service area boundaries with sensitized candidates can be influenced by HLA C. Clin Transplant. 2010 Jan-Feb; 24(1):56-61. PMID: 20015269.
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    65. Schadde E, D'Alessandro AM, Knechtle SJ, Odorico J, Becker Y, Pirsch J, Sollinger H, Fernandez LA. Alemtuzumab induction and triple maintenance immunotherapy in kidney transplantation from donors after cardiac death. Transpl Int. 2008 Jul; 21(7):625-36. PMID: 18397178.
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    66. Kwun J, Hu H, Schadde E, Roenneburg D, Sullivan KA, DeMartino J, Burlingham WJ, Knechtle SJ. Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients. J Immunol. 2007 Dec 15; 179(12):8016-25. PMID: 18056341.
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    67. Schadde E, d'Alessandro AM, Musat AI, Torrealba JR, Knechtle SJ. Donor-specific HLA-antibody-mediated humoral rejection in a liver transplant recipient fully reversed with plasmapheresis and immunoglobulin. Clin Transpl. 2006; 479-82. PMID: 18365407.
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    68. Samaniego M, Mezrich J, Torrealba J, Lorentzen D, Schadde E, Djamali A, Zachariah M, Sollinger H, Pirsch J. C4d-positive acute antibody-mediated rejection due to anti-HLA-DP antibody: a tale of one patient and a review of the University of Wisconsin experience. Clin Transpl. 2006; 503-7. PMID: 18365412.
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    69. Schadde E. Wild life: Spirituality in medicine. Curr Surg. 2004 Sep-Oct; 61(5):484-6. PMID: 15475102.
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