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Alejandro Espinoza-Orias

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentOrthopedic Surgery
Address1611 W. Harrison St.
Chicago IL 60612
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    Alejandro A. Espinoza Orias, PhD, received a licentiate degree in mechanical engineering degree from the Universidad Mayor de San Andres (La Paz, Bolivia) in addition to master’s and doctoral degrees in aerospace and mechanical engineering at the University of Notre Dame (Notre Dame, Indiana). He later completed a postdoctoral fellowship in spine biomechanics at the McKay orthopedic research laboratory at the University of Pennsylvania (Philadelphia, Pennsylvania, USA). He is an assistant professor in the Department of Orthopedic Surgery at Rush University Medical Center (Chicago). His research interests include joint biomechanics, the study of structure-function relationships in orthopedic materials and tissues and applications of 3-D printing in orthopedics.

    Espinoza Orias is an active member of the Orthopaedic Research Society, American Society of Mechanical Engineers, American Society for Testing and Materials International, and Sigma Xi, the Scientific Research Society, He conducts peer review on many orthopedic and biomechanics journals and is on the editorial board of PLoS One.

    My ORCID is 0000-0002-3792-515X.
    My Scopus ID is 57188703592.
    My NIH COMMONS name is AESPINOZA

    Education
    Postdoctoral fellowship, McKay Orthopaedic Research Lab, Perelman School of Medicine, University of Pennsylvania, 2007
    PhD, aerospace and mechanical engineering, University of Notre Dame, 2005
    MSc, mechanical engineering, University of Notre Dame, 2003
    BSc (Licentiate), mechanical engineering, Universidad Mayor de San Andres, Bolivia, 1999


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Louie PK, Espinoza Orías AA, Fogg LF, LaBelle M, An HS, Andersson GBJ. Changes in Lumbar Endplate Area and Concavity Associated With Disc Degeneration. Spine (Phila Pa 1976). 2018 Oct 01; 43(19):E1127-E1134. PMID: 29596278.
      View in: PubMed
    2. Yang SH, Espinoza Orías AA, Pan CC, Senoo I, Andersson GBJ, An HS, Inoue N. Spatial geometric and magnetic resonance signal intensity changes with advancing stages of nucleus pulposus degeneration. BMC Musculoskelet Disord. 2017 Nov 21; 18(1):473. PMID: 29162082.
      View in: PubMed
    3. Basques BA, Espinoza Orías AA, Shifflett GD, Fice MP, Andersson GB, An HS, Inoue N. The Kinematics and Spondylosis of the Lumbar Spine Vary Depending on the Levels of Motion Segments in Individuals With Low Back Pain. Spine (Phila Pa 1976). 2017 Jul 01; 42(13):E767-E774. PMID: 27831966.
      View in: PubMed
    4. Kishimoto M, Akeda K, Sudo A, Espinoza Orías AA, Inoue N. In vivo measurement of vertebral endplate surface area along the whole-spine. J Orthop Res. 2016 08; 34(8):1418-30. PMID: 27346338.
      View in: PubMed
    5. Zhou J, Espinoza Orías AA, Kang X, He J, Zhang Z, Inoue N, An HS. CT-based morphometric analysis of the occipital condyle: focus on occipital condyle screw insertion. J Neurosurg Spine. 2016 Nov; 25(5):572-579. PMID: 27341056.
      View in: PubMed
    6. Wuerz TH, Song SH, Grzybowski JS, Martin HD, Mather RC, Salata MJ, Espinoza Orías AA, Nho SJ. Capsulotomy Size Affects Hip Joint Kinematic Stability. Arthroscopy. 2016 08; 32(8):1571-80. PMID: 27212048.
      View in: PubMed
    7. Espinoza Orías AA, Mammoser NM, Triano JJ, An HS, Andersson GB, Inoue N. Effects of Axial Torsion on Disc Height Distribution: An In Vivo Study. J Manipulative Physiol Ther. 2016 05; 39(4):294-303. PMID: 27059249.
      View in: PubMed
    8. Farkas GJ, Cvetanovich GL, Rajan KB, Espinoza Orías AA, Nho SJ. Impact of Femoroacetabular Impingement Morphology on Gait Assessment in Symptomatic Patients. Sports Health. 2015 Sep-Oct; 7(5):429-36. PMID: 26502419; PMCID: PMC4547117.
    9. Munns JJ, Lee JY, Espinoza Orías AA, Takatori R, Andersson GB, An HS, Inoue N. Ligamentum flavum hypertrophy in asymptomatic and chronic low back pain subjects. PLoS One. 2015; 10(5):e0128321. PMID: 26010138; PMCID: PMC4444243.
    10. Abrams GD, Hart MA, Takami K, Bayne CO, Kelly BT, Espinoza Orías AA, Nho SJ. Biomechanical Evaluation of Capsulotomy, Capsulectomy, and Capsular Repair on Hip Rotation. Arthroscopy. 2015 Aug; 31(8):1511-7. PMID: 25882176.
      View in: PubMed
    11. Yamaguchi T, Goto S, Nishigaki Y, Espinoza Orías AA, Bae WC, Masuda K, Inoue N. Microstructural analysis of three-dimensional canal network in the rabbit lumbar vertebral endplate. J Orthop Res. 2015 Feb; 33(2):270-6. PMID: 25367593.
      View in: PubMed
    12. Senoo I, Espinoza Orías AA, An HS, Andersson GB, Park DK, Triano JJ, Inoue N. In vivo 3-dimensional morphometric analysis of the lumbar foramen in healthy subjects. Spine (Phila Pa 1976). 2014 Jul 15; 39(16):E929-35. PMID: 24825158; PMCID: PMC4111842.
    13. Bayne CO, Stanley R, Simon P, Espinoza-Orias A, Salata MJ, Bush-Joseph CA, Inoue N, Nho SJ. Effect of capsulotomy on hip stability-a consideration during hip arthroscopy. Am J Orthop (Belle Mead NJ). 2014 Apr; 43(4):160-5. PMID: 24730000.
      View in: PubMed
    14. Hong JT, Qasim M, Espinoza Orías AA, Natarajan RN, An HS. A biomechanical comparison of three different posterior fixation constructs used for c6-c7 cervical spine immobilization: a finite element study. Neurol Med Chir (Tokyo). 2014; 54(9):727-35. PMID: 24418790; PMCID: PMC4533369.
    15. O'Keefe JA, Espinoza Orías AA, Khan H, Hall DA, Berry-Kravis E, Wimmer MA. Implementation of a markerless motion analysis method to quantify hyperkinesis in males with fragile X syndrome. Gait Posture. 2014 Feb; 39(2):827-30. PMID: 24252602.
      View in: PubMed
    16. Nho SJ, Freedman RL, Federer AE, Mather RC, Espinoza Orias AA, Wang VM, Van Thiel GS. Computed tomographic analysis of curved and straight guides for placement of suture anchors for acetabular labral refixation. Arthroscopy. 2013 Oct; 29(10):1623-7. PMID: 24075612.
      View in: PubMed
    17. Kang RW, Yanke AB, Espinoza Orias AA, Orias AE, Inoue N, Nho SJ. Emerging ideas: Novel 3-D quantification and classification of cam lesions in patients with femoroacetabular impingement. Clin Orthop Relat Res. 2013 Feb; 471(2):358-62. PMID: 23129477; PMCID: PMC3549194.
    18. Frank RM, Alland J, Grumet RC, Slabaugh MA, Williams JM, Wang VM, Espinoza Orias AA, Bach BR, Nho SJ. Hip osseous morphology using computer navigation and plain radiographs. Am J Orthop (Belle Mead NJ). 2012 Nov; 41(11):519-25. PMID: 23431516.
      View in: PubMed
    19. Showalter BL, Beckstein JC, Martin JT, Beattie EE, Espinoza Orías AA, Schaer TP, Vresilovic EJ, Elliott DM. Comparison of animal discs used in disc research to human lumbar disc: torsion mechanics and collagen content. Spine (Phila Pa 1976). 2012 Jul 01; 37(15):E900-7. PMID: 22333953; PMCID: PMC3377819.
    20. Takigawa T, Simon P, Espinoza Orías AA, Hong JT, Ito Y, Inoue N, An HS. Biomechanical comparison of occiput-C1-C2 fixation techniques: C0-C1 transarticular screw and direct occiput condyle screw. Spine (Phila Pa 1976). 2012 May 20; 37(12):E696-701. PMID: 22158063.
      View in: PubMed
    21. Simon P, Espinoza Orías AA, Andersson GB, An HS, Inoue N. In vivo topographic analysis of lumbar facet joint space width distribution in healthy and symptomatic subjects. Spine (Phila Pa 1976). 2012 May 20; 37(12):1058-64. PMID: 22433501; PMCID: PMC3685171.
    22. Watanabe S, Inoue N, Yamaguchi T, Hirano Y, Espinoza Orías AA, Nishida S, Hirose Y, Mizuno J. Three-dimensional kinematic analysis of the cervical spine after anterior cervical decompression and fusion at an adjacent level: a preliminary report. Eur Spine J. 2012 May; 21(5):946-55. PMID: 22124708; PMCID: PMC3337902.
    23. Inoue N, Espinoza Orías AA. Biomechanics of intervertebral disk degeneration. Orthop Clin North Am. 2011 Oct; 42(4):487-99, vii. PMID: 21944586; PMCID: PMC3183968.
    24. Bhatia A, Albazzaz M, Espinoza Orías AA, Inoue N, Miller LM, Acerbo A, George A, Sumner DR. Overexpression of DMP1 accelerates mineralization and alters cortical bone biomechanical properties in vivo. J Mech Behav Biomed Mater. 2012 Jan; 5(1):1-8. PMID: 22100074; PMCID: PMC3222863.
    25. Hong JT, Takigawa T, Udayakunmar R, Shin HK, Simon P, Espinoza Orías AA, Inoue N, An HS. Biomechanical effect of the C2 laminar decortication on the stability of C2 intralaminar screw construct and biomechanical comparison of C2 intralaminar screw and C2 pars screw. Neurosurgery. 2011 Sep; 69(1 Suppl Operative):ons1-6; discussion ons6-7. PMID: 21415794.
      View in: PubMed
    26. Rudy DJ, Deuerling JM, Espinoza Orías AA, Roeder RK. Anatomic variation in the elastic inhomogeneity and anisotropy of human femoral cortical bone tissue is consistent across multiple donors. J Biomech. 2011 Jun 03; 44(9):1817-20. PMID: 21543070; PMCID: PMC3111152.
    27. Hong JT, Tomoyuki T, Udayakumar R, Espinoza Orías AA, Inoue N, An HS. Biomechanical comparison of three different types of C7 fixation techniques. Spine (Phila Pa 1976). 2011 Mar 01; 36(5):393-8. PMID: 21325933.
      View in: PubMed
    28. Piasecki DP, Bach BR, Espinoza Orias AA, Verma NN. Anterior cruciate ligament reconstruction: can anatomic femoral placement be achieved with a transtibial technique? Am J Sports Med. 2011 Jun; 39(6):1306-15. PMID: 21335345.
      View in: PubMed
    29. Hong JT, Takigawa T, Sugisaki K, Espinoza Orías AA, Inoue N, An HS. Biomechanical and morphometric evaluation of occipital condyle for occipitocervical segmental fixation. Neurol Med Chir (Tokyo). 2011; 51(10):701-6. PMID: 22027245.
      View in: PubMed
    30. Duan CY, Espinoza Orías AA, Shott S, An HS, Andersson GB, Hu JZ, Lu HB, Inoue N. In vivo measurement of the subchondral bone thickness of lumbar facet joint using magnetic resonance imaging. Osteoarthritis Cartilage. 2011 Jan; 19(1):96-102. PMID: 21034837; PMCID: PMC3011863.
    31. Takigawa T, Espinoza Orías AA, An HS, Gohgi S, Udayakumar RK, Sugisaki K, Natarajan RN, Wimmer MA, Inoue N. Spinal kinematics and facet load transmission after total disc replacement. Spine (Phila Pa 1976). 2010 Oct 15; 35(22):E1160-6. PMID: 20881657.
      View in: PubMed
    32. Otsuka Y, An HS, Ochia RS, Andersson GB, Espinoza Orías AA, Inoue N. In vivo measurement of lumbar facet joint area in asymptomatic and chronic low back pain subjects. Spine (Phila Pa 1976). 2010 Apr 15; 35(8):924-8. PMID: 20354471; PMCID: PMC2855783.
    33. Ritacco LE, Espinoza Orías AA, Aponte-Tinao L, Muscolo DL, de Quirós FG, Nozomu I. Three-dimensional morphometric analysis of the distal femur: a validity method for allograft selection using a virtual bone bank. Stud Health Technol Inform. 2010; 160(Pt 2):1287-90. PMID: 20841892.
      View in: PubMed
    34. Sugisaki K, An HS, Espinoza Orías AA, Rhim R, Andersson GB, Inoue N. In vivo three-dimensional morphometric analysis of the lumbar pedicle isthmus. Spine (Phila Pa 1976). 2009 Nov 15; 34(24):2599-604. PMID: 19910763; PMCID: PMC2810254.
    35. Deuerling JM, Yue W, Espinoza Orías AA, Roeder RK. Specimen-specific multi-scale model for the anisotropic elastic constants of human cortical bone. J Biomech. 2009 Sep 18; 42(13):2061-7. PMID: 19664772; PMCID: PMC2770098.
    36. Espinoza Orías AA, Deuerling JM, Landrigan MD, Renaud JE, Roeder RK. Anatomic variation in the elastic anisotropy of cortical bone tissue in the human femur. J Mech Behav Biomed Mater. 2009 Jul; 2(3):255-63. PMID: 19627830; PMCID: PMC2702870.
    37. Espinoza Orías AA, Malhotra NR, Elliott DM. Rat disc torsional mechanics: effect of lumbar and caudal levels and axial compression load. Spine J. 2009 Mar; 9(3):204-9. PMID: 18495544; PMCID: PMC2724720.
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