 CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
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| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
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| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
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Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 4 | 5 | | 1991 | 0 | 3 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 2 | 0 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 2 | 1 | 3 | | 1997 | 2 | 1 | 3 | | 1998 | 1 | 0 | 1 | | 1999 | 4 | 0 | 4 | | 2000 | 3 | 6 | 9 | | 2001 | 4 | 3 | 7 | | 2002 | 2 | 3 | 5 | | 2003 | 1 | 5 | 6 | | 2004 | 3 | 4 | 7 | | 2005 | 3 | 1 | 4 | | 2006 | 6 | 2 | 8 | | 2007 | 3 | 1 | 4 | | 2008 | 4 | 3 | 7 | | 2009 | 1 | 5 | 6 | | 2010 | 2 | 1 | 3 | | 2011 | 5 | 2 | 7 | | 2012 | 6 | 4 | 10 | | 2013 | 7 | 1 | 8 | | 2014 | 7 | 6 | 13 | | 2015 | 2 | 4 | 6 | | 2016 | 4 | 7 | 11 | | 2017 | 0 | 2 | 2 | | 2018 | 3 | 2 | 5 | | 2019 | 3 | 3 | 6 | | 2020 | 1 | 3 | 4 | | 2021 | 4 | 3 | 7 | | 2022 | 0 | 6 | 6 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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Gianella S, Rawlings SA, Dobrowolski C, Nakazawa M, Chaillon A, Strain M, Layman L, Caballero G, Scully E, Scott B, Pacis C, Weber KM, Landay A, Anderson C, Karn J. Sex Differences in Human Immunodeficiency Virus Persistence and Reservoir Size During Aging. Clin Infect Dis. 2022 08 24; 75(1):73-80.
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Feinstein MJ, Buzkova P, Olson NC, Doyle MF, Sitlani CM, Fohner AE, Huber SA, Floyd J, Sinha A, Thorp EB, Landay A, Freiberg MS, Longstreth WT, Tracy RP, Psaty BM, Delaney JA. Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study. Atherosclerosis. 2022 06; 351:18-25.
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Bailin SS, Kundu S, Wellons M, Freiberg MS, Doyle MF, Tracy RP, Justice AC, Wanjalla CN, Landay AL, So-Armah K, Mallal S, Kropski JA, Koethe JR. Circulating CD4+ TEMRA and CD4+ CD28- T cells and incident diabetes among persons with and without HIV. AIDS. 2022 03 15; 36(4):501-511.
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Barbian HJ, Seaton MS, Narasipura SD, Wallace J, Rajan R, Sha BE, Al-Harthi L. ?-catenin regulates HIV latency and modulates HIV reactivation. PLoS Pathog. 2022 03; 18(3):e1010354.
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Peters BA, Moon JY, Hanna DB, Kutsch O, Fischl M, Moran CA, Adimora AA, Gange S, Roan NR, Michel KG, Augenbraun M, Sharma A, Landay A, Desai S, Kaplan RC. T-Cell Immune Dysregulation and Mortality in Women With Human Immunodeficiency Virus. J Infect Dis. 2022 02 15; 225(4):675-685.
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Kundu M, Raha S, Roy A, Pahan K. Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2).
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Schroeder BA, LaFranzo NA, LaFleur BJ, Gittelman RM, Vignali M, Zhang S, Flanagan KC, Rytlewski J, Riolobos L, Schulte BC, Kim TS, Chen E, Smythe KS, Wagner MJ, Mantilla JG, Campbell JS, Pierce RH, Jones RL, Cranmer LD, Pollack SM. CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes. J Immunother Cancer. 2021 08; 9(8).
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Zhao J, Wang L, Schank M, Dang X, Lu Z, Cao D, Khanal S, Nguyen LN, Nguyen LNT, Zhang J, Zhang Y, Adkins JL, Baird EM, Wu XY, Ning S, Gazzar ME, Moorman JP, Yao ZQ. SARS-CoV-2 specific memory T cell epitopes identified in COVID-19-recovered subjects. Virus Res. 2021 10 15; 304:198508.
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Le Hingrat Q, Sereti I, Landay AL, Pandrea I, Apetrei C. The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection. Front Immunol. 2021; 12:695674.
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Zhao J, Schank M, Wang L, Li Z, Nguyen LN, Dang X, Cao D, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Liu Y, Zhang J, Ning S, Moorman JP, Yao ZQ. Mitochondrial Functions Are Compromised in CD4 T Cells From ART-Controlled PLHIV. Front Immunol. 2021; 12:658420.
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