CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 2 | 2 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 3 | 3 | 6 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 3 | 1 | 4 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 4 | 1 | 5 |
| 2012 | 3 | 4 | 7 |
| 2013 | 4 | 2 | 6 |
| 2014 | 4 | 4 | 8 |
| 2015 | 0 | 4 | 4 |
| 2016 | 2 | 5 | 7 |
| 2017 | 0 | 1 | 1 |
| 2019 | 2 | 2 | 4 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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CD4 dim CD8 bright T cells are inversely associated with neuro-inflammatory markers among people with HIV. AIDS. 2024 Jan 01; 38(1):1-7.
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T cell activation is insufficient to drive SIV disease progression. JCI Insight. 2023 07 24; 8(14).
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Neuro-PASC is characterized by enhanced CD4+ and diminished CD8+ T cell responses to SARS-CoV-2 Nucleocapsid protein. Front Immunol. 2023; 14:1155770.
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Sex Differences in Human Immunodeficiency Virus Persistence and Reservoir Size During Aging. Clin Infect Dis. 2022 08 24; 75(1):73-80.
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Wnt/?-Catenin Protects Lymphocytes from HIV-Mediated Apoptosis via Induction of Bcl-xL. Viruses. 2022 07 02; 14(7).
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Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study. Atherosclerosis. 2022 06; 351:18-25.
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Circulating CD4+ TEMRA and CD4+ CD28- T cells and incident diabetes among persons with and without HIV. AIDS. 2022 03 15; 36(4):501-511.
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?-catenin regulates HIV latency and modulates HIV reactivation. PLoS Pathog. 2022 03; 18(3):e1010354.
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T-Cell Immune Dysregulation and Mortality in Women With Human Immunodeficiency Virus. J Infect Dis. 2022 02 15; 225(4):675-685.
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Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2).