 Aspirin
"Aspirin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
| Descriptor ID |
D001241
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| MeSH Number(s) |
D02.455.426.559.389.657.410.595.176
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| Concept/Terms |
Aspirin- Aspirin
- Acetylsalicylic Acid
- Acid, Acetylsalicylic
- 2-(Acetyloxy)benzoic Acid
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Below are MeSH descriptors whose meaning is more general than "Aspirin".
Below are MeSH descriptors whose meaning is more specific than "Aspirin".
This graph shows the total number of publications written about "Aspirin" by people in this website by year, and whether "Aspirin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1987 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 4 | 5 | | 2009 | 1 | 4 | 5 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 3 | 2 | 5 | | 2018 | 7 | 0 | 7 | | 2019 | 1 | 2 | 3 |
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Below are the most recent publications written about "Aspirin" by people in Profiles.
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Manista GC, Batko BD, Sexton AC, Edmiston TA, Courtney PM, Hannon CP, Levine BR. Anticoagulation in Revision Total Joint Arthroplasty: A Retrospective Review of 1917 Cases. Orthopedics. 2019 Nov 01; 42(6):323-329.
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Mahdavinia M, Batra PS, Codispoti C. Mepolizumab utility in successful aspirin desensitization in aspirin-exacerbated respiratory disease in a refractory case. Ann Allergy Asthma Immunol. 2019 09; 123(3):311-312.
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Pahan S, Pahan K. Mode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis. DNA Cell Biol. 2019 Jul; 38(7):593-596.
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Mondal S, Jana M, Dasarathi S, Roy A, Pahan K. Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells. Sci Signal. 2018 11 27; 11(558).
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Stocks NP, González-Chica DA, Woods RL, Lockery JE, Wolfe RSJ, Murray AM, Kirpach B, Shah RC, Nelson MR, Reid CM, Ernst ME, McNeil JJ. Quality of Life for 19,114 participants in the ASPREE (ASPirin in Reducing Events in the Elderly) study and their association with sociodemographic and modifiable lifestyle risk factors. Qual Life Res. 2019 Apr; 28(4):935-946.
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McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Radziszewska B, Grimm R, Murray AM. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med. 2018 10 18; 379(16):1519-1528.
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McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Ryan J, Radziszewska B, Grimm R, Murray AM. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med. 2018 10 18; 379(16):1499-1508.
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McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, Reid CM, Lockery JE, Kirpach B, Storey E, Shah RC, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Johnston CI, Ryan J, Radziszewska B, Jelinek M, Malik M, Eaton CB, Brauer D, Cloud G, Wood EM, Mahady SE, Satterfield S, Grimm R, Murray AM. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. N Engl J Med. 2018 10 18; 379(16):1509-1518.
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Patel D, Roy A, Kundu M, Jana M, Luan CH, Gonzalez FJ, Pahan K. Aspirin binds to PPARa to stimulate hippocampal plasticity and protect memory. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):E7408-E7417.
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Chandra S, Jana M, Pahan K. Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARa. J Neurosci. 2018 07 25; 38(30):6682-6699.
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