 Aspirin
"Aspirin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
| Descriptor ID |
D001241
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| MeSH Number(s) |
D02.455.426.559.389.657.410.595.176
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| Concept/Terms |
Aspirin- Aspirin
- Acetylsalicylic Acid
- Acid, Acetylsalicylic
- 2-(Acetyloxy)benzoic Acid
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Below are MeSH descriptors whose meaning is more general than "Aspirin".
Below are MeSH descriptors whose meaning is more specific than "Aspirin".
This graph shows the total number of publications written about "Aspirin" by people in this website by year, and whether "Aspirin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1987 | 1 | 0 | 1 | | 1989 | 1 | 0 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 4 | 5 | | 2009 | 1 | 4 | 5 | | 2010 | 3 | 1 | 4 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 3 | 2 | 5 | | 2018 | 8 | 0 | 8 | | 2019 | 4 | 2 | 6 | | 2020 | 4 | 1 | 5 | | 2021 | 2 | 1 | 3 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aspirin" by people in Profiles.
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Ryan J, Espinoza S, Ernst ME, Ekram ARMS, Wolfe R, Murray AM, Shah RC, Orchard SG, Fitzgerald S, Beilin LJ, Ward SA, Williamson JD, Newman AB, McNeil JJ, Woods RL. Validation of a Deficit-Accumulation Frailty Index in the ASPirin in Reducing Events in the Elderly Study and Its Predictive Capacity for Disability-Free Survival. J Gerontol A Biol Sci Med Sci. 2022 01 07; 77(1):19-26.
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Woods RL, Espinoza S, Thao LTP, Ernst ME, Ryan J, Wolfe R, Shah RC, Ward SA, Storey E, Nelson MR, Reid CM, Lockery JE, Orchard SG, Trevaks RE, Fitzgerald SM, Stocks NP, Williamson JD, McNeil JJ, Murray AM, Newman AB. Effect of Aspirin on Activities of Daily Living Disability in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2021 10 13; 76(11):2007-2014.
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McNeil JJ, Gibbs P, Orchard SG, Lockery JE, Bernstein WB, Cao Y, Ford L, Haydon A, Kirpach B, Macrae F, McLean C, Millar J, Murray AM, Nelson MR, Polekhina G, Reid CM, Richmond E, RodrÃguez LM, Shah RC, Tie J, Umar A, Londen GJV, Ronaldson K, Wolfe R, Woods RL, Zalcberg J, Chan AT. Effect of Aspirin on Cancer Incidence and Mortality in Older Adults. J Natl Cancer Inst. 2021 03 01; 113(3):258-265.
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Berk M, Agustini B, Woods RL, Nelson MR, Shah RC, Reid CM, Storey E, Fitzgerald SM, Lockery JE, Wolfe R, Mohebbi M, Dodd S, Murray AM, Stocks N, Fitzgerald PB, Mazza C, McNeil JJ. Effects of aspirin on the long-term management of depression in older people: a double-blind randomised placebo-controlled trial. Mol Psychiatry. 2021 09; 26(9):5161-5170.
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Berk M, Woods RL, Nelson MR, Shah RC, Reid CM, Storey E, Fitzgerald S, Lockery JE, Wolfe R, Mohebbi M, Dodd S, Murray AM, Stocks N, Fitzgerald PB, Mazza C, Agustini B, McNeil JJ. Effect of Aspirin vs Placebo on the Prevention of Depression in Older People: A Randomized Clinical Trial. JAMA Psychiatry. 2020 10 01; 77(10):1012-1020.
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Wolfe R, Wetmore JB, Woods RL, McNeil JJ, Gallagher H, Roderick P, Walker R, Nelson MR, Reid CM, Shah RC, Ernst ME, Lockery JE, Tonkin AM, Abhayaratna WP, Gibbs P, Wood EM, Mahady SE, Williamson JD, Donnan GA, Cloud GC, Murray AM, Polkinghorne KR. Subgroup analysis of the ASPirin in Reducing Events in the Elderly randomized clinical trial suggests aspirin did not improve outcomes in older adults with chronic kidney disease. Kidney Int. 2021 02; 99(2):466-474.
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Woods RL, Polekhina G, Wolfe R, Nelson MR, Ernst ME, Reid CM, Shah RC, Lockery JE, Orchard SG, Murray AM, McNeil JJ. No Modulation of the Effect of Aspirin by Body Weight in Healthy Older Men and Women. Circulation. 2020 03 31; 141(13):1110-1112.
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Ryan J, Storey E, Murray AM, Woods RL, Wolfe R, Reid CM, Nelson MR, Chong TTJ, Williamson JD, Ward SA, Lockery JE, Orchard SG, Trevaks R, Kirpach B, Newman AB, Ernst ME, McNeil JJ, Shah RC. Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline. Neurology. 2020 07 21; 95(3):e320-e331.
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Camara Planek MI, Silver AJ, Volgman AS, Okwuosa TM. Exploratory Review of the Role of Statins, Colchicine, and Aspirin for the Prevention of Radiation-Associated Cardiovascular Disease and Mortality. J Am Heart Assoc. 2020 01 21; 9(2):e014668.
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Patel D, Roy A, Pahan K. PPARa serves as a new receptor of aspirin for neuroprotection. J Neurosci Res. 2020 04; 98(4):626-631.
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