Interleukin-8
"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
Descriptor ID |
D016209
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MeSH Number(s) |
D12.644.276.374.200.120.800 D12.644.276.374.465.508 D12.776.467.374.200.120.800 D12.776.467.374.465.508 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.508
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Concept/Terms |
Interleukin-8- Interleukin-8
- Interleukin 8
- IL8
- Monocyte-Derived Neutrophil Chemotactic Factor
- Neutrophil Activation Factor
- Neutrophil-Activating Peptide, Lymphocyte-Derived
- Lymphocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Lymphocyte Derived
- Neutrophil-Activating Peptide, Monocyte-Derived
- Monocyte-Derived Neutrophil-Activating Peptide
- Neutrophil Activating Peptide, Monocyte Derived
- Alveolar Macrophage Chemotactic Factor-I
- Alveolar Macrophage Chemotactic Factor I
- Granulocyte Chemotactic Peptide-Interleukin-8
- Chemotactic Peptide-Interleukin-8, Granulocyte
- Granulocyte Chemotactic Peptide Interleukin 8
- Anionic Neutrophil-Activating Peptide
- Anionic Neutrophil Activating Peptide
- Neutrophil-Activating Peptide, Anionic
- Peptide, Anionic Neutrophil-Activating
- Chemokine CXCL8
- CXCL8, Chemokine
- Chemokines, CXCL8
- CXCL8 Chemokines
- Chemotactic Factor, Macrophage-Derived
- Chemotactic Factor, Macrophage Derived
- Macrophage-Derived Chemotactic Factor
- Chemotactic Factor, Neutrophil
- Neutrophil Chemotactic Factor
- Chemotactic Factor, Neutrophil, Monocyte-Derived
- CXCL8 Chemokine
- Chemokine, CXCL8
- IL-8
- AMCF-I
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Below are MeSH descriptors whose meaning is more general than "Interleukin-8".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".
This graph shows the total number of publications written about "Interleukin-8" by people in this website by year, and whether "Interleukin-8" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 2 | 2 | 1999 | 1 | 1 | 2 | 2000 | 0 | 1 | 1 | 2002 | 1 | 1 | 2 | 2004 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 | 2006 | 0 | 2 | 2 | 2007 | 0 | 2 | 2 | 2008 | 1 | 1 | 2 | 2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2015 | 3 | 0 | 3 | 2016 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-8" by people in Profiles.
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Lopez-Silva C, Surapaneni A, Coresh J, Reiser J, Parikh CR, Obeid W, Grams ME, Chen TK. Comparison of Aptamer-Based and Antibody-Based Assays for Protein Quantification in Chronic Kidney Disease. Clin J Am Soc Nephrol. 2022 03; 17(3):350-360.
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Robinson KF, Narasipura SD, Wallace J, Ritz EM, Al-Harthi L. Negative regulation of IL-8 in human astrocytes depends on ß-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction. Cytokine. 2020 12; 136:155252.
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Zhang Y, Chee A, Shi P, Adams SL, Markova DZ, Anderson DG, Smith HE, Deng Y, Plastaras CT, An HS. Intervertebral Disc Cells Produce Interleukins Found in Patients with Back Pain. Am J Phys Med Rehabil. 2016 06; 95(6):407-15.
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Zhang Y, Chee A, Shi P, Wang R, Moss I, Chen EY, He TC, An HS. Allogeneic Articular Chondrocyte Transplantation Downregulates Interleukin 8 Gene Expression in the Degenerating Rabbit Intervertebral Disk In Vivo. Am J Phys Med Rehabil. 2015 Jul; 94(7):530-8.
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Jarrett OD, Brady KE, Modur SP, Plants J, Landay AL, Ghassemi M, Golub ET, Spear GT, Novak RM. T. vaginalis Infection Is Associated with Increased IL-8 and TNFr1 Levels but with the Absence of CD38 and HLADR Activation in the Cervix of ESN. PLoS One. 2015; 10(6):e0130146.
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Zariffard MR, Anastos K, French AL, Munyazesa E, Cohen M, Landay AL, Spear GT. Cleavage/alteration of interleukin-8 by matrix metalloproteinase-9 in the female lower genital tract. PLoS One. 2015; 10(1):e0116911.
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Gao L, Wu GJ, Liu XW, Zhang R, Yu L, Zhang G, Liu F, Yu CG, Yuan JL, Wang H, Yao LB. Suppression of invasion and metastasis of prostate cancer cells by overexpression of NDRG2 gene. Cancer Lett. 2011 Nov 01; 310(1):94-100.
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Ghorbel MT, Cherif M, Mokhtari A, Bruno VD, Caputo M, Angelini GD. Off-pump coronary artery bypass surgery is associated with fewer gene expression changes in the human myocardium in comparison with on-pump surgery. Physiol Genomics. 2010 Jun; 42(1):67-75.
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Keithi-Reddy SR, Addabbo F, Patel TV, Mittal BV, Goligorsky MS, Singh AK. Association of anemia and erythropoiesis stimulating agents with inflammatory biomarkers in chronic kidney disease. Kidney Int. 2008 Sep; 74(6):782-90.
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Spear GT, Zariffard MR, Cohen MH, Sha BE. Vaginal IL-8 levels are positively associated with Candida albicans and inversely with lactobacilli in HIV-infected women. J Reprod Immunol. 2008 Jun; 78(1):76-9.
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