 Decorin
"Decorin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
| Descriptor ID |
D058575
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| MeSH Number(s) |
D12.776.395.650.750.625
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| Concept/Terms |
Decorin- Decorin
- Bone Proteoglycan II
- II, Bone Proteoglycan
- Proteoglycan II, Bone
- DSPG-II
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Below are MeSH descriptors whose meaning is more general than "Decorin".
Below are MeSH descriptors whose meaning is more specific than "Decorin".
This graph shows the total number of publications written about "Decorin" by people in this website by year, and whether "Decorin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2009 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Decorin" by people in Profiles.
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McCorry MC, Kim J, Springer NL, Sandy J, Plaas A, Bonassar LJ. Regulation of proteoglycan production by varying glucose concentrations controls fiber formation in tissue engineered menisci. Acta Biomater. 2019 12; 100:173-183.
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Mazzocca AD, McCarthy MB, Ledgard FA, Chowaniec DM, McKinnon WJ, Delaronde S, Rubino LJ, Apolostakos J, Romeo AA, Arciero RA, Beitzel K. Histomorphologic changes of the long head of the biceps tendon in common shoulder pathologies. Arthroscopy. 2013 Jun; 29(6):972-81.
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Singh K, Masuda K, Thonar EJ, An HS, Cs-Szabo G. Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):10-6.
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Liu W, Burton-Wurster N, Glant TT, Tashman S, Sumner DR, Kamath RV, Lust G, Kimura JH, Cs-Szabo G. Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels. J Orthop Res. 2003 Jul; 21(4):730-7.
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Carrino DA, Onnerfjord P, Sandy JD, Cs-Szabo G, Scott PG, Sorrell JM, Heinegård D, Caplan AI. Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin. J Biol Chem. 2003 May 09; 278(19):17566-72.
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Burton-Wurster N, Liu W, Matthews GL, Lust G, Roughley PJ, Glant TT, Cs-Szabó G. TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage. Osteoarthritis Cartilage. 2003 Mar; 11(3):167-76.
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Cs-Szabo G, Ragasa-San Juan D, Turumella V, Masuda K, Thonar EJ, An HS. Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration. Spine (Phila Pa 1976). 2002 Oct 15; 27(20):2212-9.
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Soo C, Hu FY, Zhang X, Wang Y, Beanes SR, Lorenz HP, Hedrick MH, Mackool RJ, Plaas A, Kim SJ, Longaker MT, Freymiller E, Ting K. Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol. 2000 Aug; 157(2):423-33.
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Plaas AH, Wong-Palms S, Koob T, Hernandez D, Marchuk L, Frank CB. Proteoglycan metabolism during repair of the ruptured medial collateral ligament in skeletally mature rabbits. Arch Biochem Biophys. 2000 Feb 01; 374(1):35-41.
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Wong-Palms S, Plaas AH. Glycosaminoglycan addition to proteoglycans by articular chondrocytes--evidence for core protein-specific pathways. Arch Biochem Biophys. 1995 Jun 01; 319(2):383-92.
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