Core Binding Factor Alpha 2 Subunit

"Core Binding Factor Alpha 2 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.

Descriptor ID	D050676
MeSH Number(s)	D12.776.930.155.200.200
Concept/Terms	Core Binding Factor Alpha 2 Subunit Core Binding Factor Alpha 2 Subunit Runx1 Protein Pebp2a2 Protein Runt-Related Transcription Factor 1 Runt Related Transcription Factor 1 Acute Myeloid Leukemia 1 Protein Core-Binding Factor Alpha 2 Protein Core Binding Factor Alpha 2 Protein Acute Myeloid Leukemia 1D Protein Acute Myeloid Leukemia 1D Protein AML1D Protein Acute Myeloid Leukemia 1C Protein Acute Myeloid Leukemia 1C Protein AML1C Protein Acute Myeloid Leukemia 1B Protein Acute Myeloid Leukemia 1B Protein AML1B Protein Acute Myeloid Leukemia 1A Protein Acute Myeloid Leukemia 1A Protein AML1A Protein

Below are MeSH descriptors whose meaning is more general than "Core Binding Factor Alpha 2 Subunit".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Core Binding Factors [D12.776.930.155]
Core Binding Factor alpha Subunits [D12.776.930.155.200]
Core Binding Factor Alpha 2 Subunit [D12.776.930.155.200.200]

Below are MeSH descriptors whose meaning is related to "Core Binding Factor Alpha 2 Subunit".

Below are MeSH descriptors whose meaning is more specific than "Core Binding Factor Alpha 2 Subunit".

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This graph shows the total number of publications written about "Core Binding Factor Alpha 2 Subunit" by people in this website by year, and whether "Core Binding Factor Alpha 2 Subunit" was a major or minor topic of these publications.

Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 2005

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Year	Major Topic	Minor Topic	Total
2005	0	2	2
2010	1	0	1
2023	0	1	1

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