 Factor IX
"Factor IX" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).
| Descriptor ID |
D005164
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| MeSH Number(s) |
D12.776.124.125.375 D23.119.375
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| Concept/Terms |
Factor IX- Factor IX
- Christmas Factor
- Coagulation Factor IX
- Factor IX, Coagulation
- IX, Coagulation Factor
- Factor IX Fraction
- Fraction, Factor IX
- IX Fraction, Factor
- PTC
- Blood Coagulation Factor IX
- Factor IX Complex
- Complex, Factor IX
- IX Complex, Factor
- Autoprothrombin II
- Plasma Thromboplastin Component
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Below are MeSH descriptors whose meaning is more general than "Factor IX".
Below are MeSH descriptors whose meaning is more specific than "Factor IX".
This graph shows the total number of publications written about "Factor IX" by people in this website by year, and whether "Factor IX" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor IX" by people in Profiles.
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Mancuso ME, Oldenburg J, Boggio L, Kenet G, Chan A, Altisent C, Seifert W, Santagostino E. High adherence to prophylaxis regimens in haemophilia B patients receiving rIX-FP: Evidence from clinical trials and real-world practice. Haemophilia. 2020 Jul; 26(4):637-642.
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Santagostino E, Martinowitz U, Lissitchkov T, Pan-Petesch B, Hanabusa H, Oldenburg J, Boggio L, Negrier C, Pabinger I, von Depka Prondzinski M, Altisent C, Castaman G, Yamamoto K, Álvarez-Roman MT, Voigt C, Blackman N, Jacobs I. Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial. Blood. 2016 04 07; 127(14):1761-9.
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Simpson ML, Valentino LA. Management of joint bleeding in hemophilia. Expert Rev Hematol. 2012 Aug; 5(4):459-68.
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Sun J, Hakobyan N, Valentino LA, Feldman BL, Samulski RJ, Monahan PE. Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX. Blood. 2008 Dec 01; 112(12):4532-41.
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