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Williams, David
One or more keywords matched the following items that are connected to Williams, David
Item TypeName
Concept Schistosomicides
Academic Article Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
Academic Article Identification of oxadiazoles as new drug leads for the control of schistosomiasis.
Academic Article A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase.
Academic Article Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
Academic Article The redox biology of schistosome parasites and applications for drug development.
Academic Article Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents.
Academic Article Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs.
Academic Article High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis.
Academic Article The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.
Academic Article Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis.
Academic Article Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
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  • Schistosomicides