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Williams, David

One or more keywords matched the following items that are connected to Williams, David

Item Type	Name
Concept	NADH, NADPH Oxidoreductases
Academic Article	Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
Academic Article	Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade.
Academic Article	Identification of oxadiazoles as new drug leads for the control of schistosomiasis.
Academic Article	Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.
Academic Article	Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
Academic Article	Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni.
Academic Article	Thioredoxin glutathione reductase: its role in redox biology and potential as a target for drugs against neglected diseases.
Academic Article	On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.
Academic Article	Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites.
Academic Article	Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation.
Academic Article	New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni.
Academic Article	Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs.
Academic Article	High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis.
Academic Article	The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase.
Academic Article	Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.
Academic Article	Ectopic suicide inhibition of thioredoxin glutathione reductase.
Academic Article	Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis.
Academic Article	Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.
Academic Article	Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.

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