Immunoglobulin A, Secretory
"Immunoglobulin A, Secretory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).
| Descriptor ID |
D007071
|
| MeSH Number(s) |
D12.776.124.486.485.114.619.026.030 D12.776.124.790.651.114.619.026.030 D12.776.377.715.548.114.619.026.030
|
| Concept/Terms |
Immunoglobulin A, Secretory- Immunoglobulin A, Secretory
- Secretory IgA
- IgA, Exocrine
- Exocrine IgA
- SIgA
- IgA, Secretory
- Secretory Immunoglobulin A
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin A, Secretory".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin A, Secretory".
This graph shows the total number of publications written about "Immunoglobulin A, Secretory" by people in this website by year, and whether "Immunoglobulin A, Secretory" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin A, Secretory" by people in Profiles.
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Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L266-L280.
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PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure. PLoS Pathog. 2021 06; 17(6):e1009632.
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Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 04; 31(46):5422-9.
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A pilot study to determine the safety and feasibility of oropharyngeal administration of own mother's colostrum to extremely low-birth-weight infants. Adv Neonatal Care. 2010 Aug; 10(4):206-12.
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12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels. J Allergy Clin Immunol. 2008 Sep; 122(3):633-9.e3.
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Induction of mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) by oral immunization with bovine Papillomavirus-HIV-1 gp41 chimeric virus-like particles. J Virol. 2004 Aug; 78(15):8342-8.
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Evaluation of immunologic markers in cervicovaginal fluid of HIV-infected and uninfected women: implications for the immunologic response to HIV in the female genital tract. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Nov 01; 16(3):161-8.