"Lentivirus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genus of the family RETROVIRIDAE consisting of non-oncogenic retroviruses that produce multi-organ diseases characterized by long incubation periods and persistent infection. Lentiviruses are unique in that they contain open reading frames (ORFs) between the pol and env genes and in the 3' env region. Five serogroups are recognized, reflecting the mammalian hosts with which they are associated. HIV-1 is the type species.
| Descriptor ID |
D016086
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| MeSH Number(s) |
B04.820.650.589
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lentivirus".
Below are MeSH descriptors whose meaning is more specific than "Lentivirus".
This graph shows the total number of publications written about "Lentivirus" by people in this website by year, and whether "Lentivirus" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lentivirus" by people in Profiles.
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First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1. Clin Cancer Res. 2019 10 01; 25(19):5808-5817.
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First-in-Human Treatment With a Dendritic Cell-targeting Lentiviral Vector-expressing NY-ESO-1, LV305, Induces Deep, Durable Response in Refractory Metastatic Synovial Sarcoma Patient. J Immunother. 2017 10; 40(8):302-306.
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Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs. Sci Transl Med. 2015 May 27; 7(289):289ra81.
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A scalable method to concentrate lentiviral vectors pseudotyped with measles virus glycoproteins. Gene Ther. 2015 Mar; 22(3):280-5.
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Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice. EMBO Mol Med. 2013 11; 5(11):1684-97.
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Immune responses in liver-directed lentiviral gene therapy. Transl Res. 2013 Apr; 161(4):230-40.
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[Conservation of cyclophilin A interaction with the capsid of prehistoric lentiviruses]. Med Sci (Paris). 2011 Jun-Jul; 27(6-7):574-5.
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Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiol Dis. 2009 Nov; 36(2):303-11.
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Animal models of Huntington's disease. ILAR J. 2007; 48(4):356-73.
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Efficiency of lentiviral transduction during development in normal and rd mice. Mol Vis. 2006 Jul 11; 12:756-67.