"Tetrahydroisoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ISOQUINOLINES in which the nitrogen containing ring is protonated. They derive from the non-enzymatic Pictet-Spengler condensation of CATECHOLAMINES with ALDEHYDES.
| Descriptor ID |
D044005
|
| MeSH Number(s) |
D03.633.100.531.820
|
| Concept/Terms |
Tetrahydroisoquinolines- Tetrahydroisoquinolines
- Tetrahydro-Isoquinolines
- Tetrahydro Isoquinolines
- 1,2,3,4-Tetrahydroisoquinolines
|
Below are MeSH descriptors whose meaning is more general than "Tetrahydroisoquinolines".
Below are MeSH descriptors whose meaning is more specific than "Tetrahydroisoquinolines".
This graph shows the total number of publications written about "Tetrahydroisoquinolines" by people in this website by year, and whether "Tetrahydroisoquinolines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tetrahydroisoquinolines" by people in Profiles.
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Redefining the standard of care in metastatic leiomyosarcoma. Lancet Oncol. 2015 Apr; 16(4):360-2.
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A Phase II multicenter, open-label, clinical and pharmokinetic trial of PM00104 in patients with advanced Ewing Family of Tumors. Invest New Drugs. 2014 Feb; 32(1):171-7.
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Docetaxel plus trabectedin appears active in recurrent or persistent ovarian and primary peritoneal cancer after up to three prior regimens: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol. 2011 Mar; 120(3):459-63.
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Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol. 2007 Jul; 8(7):595-602.