"Hyaluronan Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
| Descriptor ID |
D000076002
|
| MeSH Number(s) |
D08.811.913.400.450.480.500
|
| Concept/Terms |
Hyaluronan Synthases- Hyaluronan Synthases
- Synthases, Hyaluronan
- Hyaluronan Synthase
- Synthase, Hyaluronan
- Hyaluronic Acid Synthetase
- Synthetase, Hyaluronic Acid
- Hyaluronate Synthetase
- Synthetase, Hyaluronate
- Hyaluronan Synthetase
- Synthetase, Hyaluronan
- Hyaluronate Synthase
- Synthase, Hyaluronate
Hyaluronan Synthase 3- Hyaluronan Synthase 3
- 3, Hyaluronan Synthase
- Synthase 3, Hyaluronan
- HAS3 Protein
- Protein, HAS3
|
Below are MeSH descriptors whose meaning is more general than "Hyaluronan Synthases".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronan Synthases".
This graph shows the total number of publications written about "Hyaluronan Synthases" by people in this website by year, and whether "Hyaluronan Synthases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hyaluronan Synthases" by people in Profiles.
-
Knockout of hyaluronan synthase 1, but not 3, impairs formation of the retrocalcaneal bursa. J Orthop Res. 2018 10; 36(10):2622-2632.
-
Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. J Orthop Res. 2018 01; 36(1):365-376.
-
Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage. Osteoarthritis Cartilage. 2015 Nov; 23(11):1879-89.
-
HAS3 underexpression as an indicator of poor prognosis in patients with urothelial carcinoma of the upper urinary tract and urinary bladder. Tumour Biol. 2015 Jul; 36(7):5441-50.
-
Cytokines and growth factors stimulate hyaluronan production: role of hyaluronan in epithelial to mesenchymal-like transition in non-small cell lung cancer. J Biomed Biotechnol. 2010; 2010:485468.
-
Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infection. Eukaryot Cell. 2007 Aug; 6(8):1486-96.