Promyelocytic Leukemia Zinc Finger Protein
"Promyelocytic Leukemia Zinc Finger Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Krupple-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.
| Descriptor ID |
D000075722
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| MeSH Number(s) |
D12.776.260.522.625 D12.776.930.375.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Promyelocytic Leukemia Zinc Finger Protein".
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This graph shows the total number of publications written about "Promyelocytic Leukemia Zinc Finger Protein" by people in this website by year, and whether "Promyelocytic Leukemia Zinc Finger Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Promyelocytic Leukemia Zinc Finger Protein" by people in Profiles.
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Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. EMBO J. 2019 07 15; 38(14):e101260.
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Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils. JCI Insight. 2019 03 21; 4(6).