AlkB Homolog 1, Histone H2a Dioxygenase
"AlkB Homolog 1, Histone H2a Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS.
| Descriptor ID |
D000071498
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| MeSH Number(s) |
D08.811.074.062.500 D08.811.682.690.416.139.500
|
| Concept/Terms |
AlkB Homolog 1, Histone H2a Dioxygenase- AlkB Homolog 1, Histone H2a Dioxygenase
- Alkylated DNA Repair Protein AlkB Homolog 1
- DNA Lyase ABH1
- ABH1, DNA Lyase
- ALKBH Protein
- DNA Oxidative Demethylase ALKBH1
- Alpha-Ketoglutarate-Dependent Dioxygenase ABH1
- ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase
- Alpha Ketoglutarate Dependent Dioxygenase ABH1
|
Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 1, Histone H2a Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "AlkB Homolog 1, Histone H2a Dioxygenase".
This graph shows the total number of publications written about "AlkB Homolog 1, Histone H2a Dioxygenase" by people in this website by year, and whether "AlkB Homolog 1, Histone H2a Dioxygenase" was a major or minor topic of these publications.
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Below are the most recent publications written about "AlkB Homolog 1, Histone H2a Dioxygenase" by people in Profiles.
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ALKBH1 reduces DNA N6-methyladenine to allow for vascular calcification in chronic kidney disease. J Clin Invest. 2021 07 15; 131(14).