"Forkhead Box Protein O3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A forkhead box transcription factor and transcriptional activator which triggers type 1 programmed cell death (APOPTOSIS) in the absence of APOPTOSIS INHIBITING PROTEINS, including neuronal cell death induced by OXIDATIVE STRESS. It recognizes and binds to the DNA sequence 5'-(AG)TAAA(TC)A-3' and also functions in post-transcriptional regulation of the c-MYC PROTO-ONCOGENE.
| Descriptor ID |
D000071316
|
| MeSH Number(s) |
D12.776.260.950.249.125 D12.776.930.977.249.125
|
| Concept/Terms |
Forkhead Box Protein O3- Forkhead Box Protein O3
- Forkhead in Rhabdomyosarcoma-Like 1 Protein
- Forkhead in Rhabdomyosarcoma Like 1 Protein
- FOXO3 Protein
- Protein, FOXO3
|
Below are MeSH descriptors whose meaning is more general than "Forkhead Box Protein O3".
Below are MeSH descriptors whose meaning is more specific than "Forkhead Box Protein O3".
This graph shows the total number of publications written about "Forkhead Box Protein O3" by people in this website by year, and whether "Forkhead Box Protein O3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Forkhead Box Protein O3" by people in Profiles.
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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest. 2017 Apr 03; 127(4):1271-1283.
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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.
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Cis-parinaric acid effects, cytotoxicity, c-Jun N-terminal protein kinase, forkhead transcription factor and Mn-SOD differentially in malignant and normal astrocytes. Neurochem Res. 2007 Jan; 32(1):115-24.