"Certolizumab Pegol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
| Descriptor ID |
D000068582
|
| MeSH Number(s) |
D05.750.741.125 D12.644.541.500.650.250 D12.776.124.486.485.114.224.060.500 D12.776.124.486.485.680.650.250 D12.776.124.790.651.114.224.060.500 D12.776.124.790.651.680.650.250 D12.776.377.715.548.114.224.200.500 D12.776.377.715.548.680.650.250
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Certolizumab Pegol".
- Chemicals and Drugs [D]
- Macromolecular Substances [D05]
- Polymers [D05.750]
- Polyethylene Glycols [D05.750.741]
- Certolizumab Pegol [D05.750.741.125]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Peptide Fragments [D12.644.541]
- Immunoglobulin Fragments [D12.644.541.500]
- Immunoglobulin Fab Fragments [D12.644.541.500.650]
- Certolizumab Pegol [D12.644.541.500.650.250]
- Proteins [D12.776]
- Blood Proteins [D12.776.124]
- Immunoproteins [D12.776.124.486]
- Immunoglobulins [D12.776.124.486.485]
- Antibodies [D12.776.124.486.485.114]
- Antibodies, Monoclonal [D12.776.124.486.485.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.124.486.485.114.224.060]
- Certolizumab Pegol [D12.776.124.486.485.114.224.060.500]
- Immunoglobulin Fragments [D12.776.124.486.485.680]
- Immunoglobulin Fab Fragments [D12.776.124.486.485.680.650]
- Certolizumab Pegol [D12.776.124.486.485.680.650.250]
- Serum Globulins [D12.776.124.790]
- Immunoglobulins [D12.776.124.790.651]
- Antibodies [D12.776.124.790.651.114]
- Antibodies, Monoclonal [D12.776.124.790.651.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.124.790.651.114.224.060]
- Certolizumab Pegol [D12.776.124.790.651.114.224.060.500]
- Immunoglobulin Fragments [D12.776.124.790.651.680]
- Immunoglobulin Fab Fragments [D12.776.124.790.651.680.650]
- Certolizumab Pegol [D12.776.124.790.651.680.650.250]
- Globulins [D12.776.377]
- Serum Globulins [D12.776.377.715]
- Immunoglobulins [D12.776.377.715.548]
- Antibodies [D12.776.377.715.548.114]
- Antibodies, Monoclonal [D12.776.377.715.548.114.224]
- Antibodies, Monoclonal, Humanized [D12.776.377.715.548.114.224.200]
- Certolizumab Pegol [D12.776.377.715.548.114.224.200.500]
- Immunoglobulin Fragments [D12.776.377.715.548.680]
- Immunoglobulin Fab Fragments [D12.776.377.715.548.680.650]
- Certolizumab Pegol [D12.776.377.715.548.680.650.250]
Below are MeSH descriptors whose meaning is more specific than "Certolizumab Pegol".
This graph shows the total number of publications written about "Certolizumab Pegol" by people in this website by year, and whether "Certolizumab Pegol" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Certolizumab Pegol" by people in Profiles.
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RAPID3 (Routine Assessment of Patient Index Data 3) severity categories and response criteria: Similar results to DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index) in the RAPID 1 (Rheumatoid Arthritis Prevention of Structural Damage) clinical trial of certolizumab pegol. Arthritis Care Res (Hoboken). 2011 Aug; 63(8):1142-9.
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Are we moving forward in the biological treatment of Crohn's disease? Time will tell. Inflamm Bowel Dis. 2006 Feb; 12(2):147-9.