"Alarmins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.
| Descriptor ID |
D000067531
|
| MeSH Number(s) |
D23.035
|
| Concept/Terms |
Alarmins- Alarmins
- Damage-Associated Molecular Pattern Molecules
- Damage Associated Molecular Pattern Molecules
- Danger-Associated Molecular Pattern Molecules
- Danger Associated Molecular Pattern Molecules
- Alarmin Proteins
- Alarmin
|
Below are MeSH descriptors whose meaning is more general than "Alarmins".
Below are MeSH descriptors whose meaning is more specific than "Alarmins".
This graph shows the total number of publications written about "Alarmins" by people in this website by year, and whether "Alarmins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alarmins" by people in Profiles.
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An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis. Semin Immunopathol. 2019 09; 41(5):583-594.