Interleukin-1 Receptor Accessory Protein
"Interleukin-1 Receptor Accessory Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.
| Descriptor ID |
D053577
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| MeSH Number(s) |
D12.776.543.750.705.852.420.300.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1 Receptor Accessory Protein".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1 Receptor Accessory Protein".
This graph shows the total number of publications written about "Interleukin-1 Receptor Accessory Protein" by people in this website by year, and whether "Interleukin-1 Receptor Accessory Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-1 Receptor Accessory Protein" by people in Profiles.
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GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP. Brain. 2015 Oct; 138(Pt 10):3076-88.