"Urocortins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.
| Descriptor ID |
D054832
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| MeSH Number(s) |
D06.472.699.857 D12.644.400.837 D12.644.548.887
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Urocortins".
Below are MeSH descriptors whose meaning is more specific than "Urocortins".
This graph shows the total number of publications written about "Urocortins" by people in this website by year, and whether "Urocortins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 2 | 0 | 2 |
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Below are the most recent publications written about "Urocortins" by people in Profiles.
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Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H689-700.
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NFAT transcription factor regulation by urocortin II in cardiac myocytes and heart failure. Am J Physiol Heart Circ Physiol. 2014 Mar; 306(6):H856-66.