"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 3 | 2 | 5 |
| 2014 | 2 | 2 | 4 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 4 | 5 |
| 2021 | 1 | 3 | 4 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Insulin resistance, cognition, and Alzheimer disease. Obesity (Silver Spring). 2023 06; 31(6):1486-1498.
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Liberal versus conservative intravenous fluid administration in pediatric diabetic ketoacidosis. Acad Emerg Med. 2022 Nov; 29(11):1399-1400.
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Pancreatic Islets Quality and Potency Cannot be Verified as Required for Drugs: Reflection on the FDA Review of a Biological License Application for Human Islets. Transplantation. 2021 12 01; 105(12):e409-e410.
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Improving Timeliness of Insulin Administration by Using an Insulin Dose Calculator. Hosp Pediatr. 2021 10; 11(10):1163-1173.
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A comparison of insulin doses for treatment of hyperkalaemia in intensive care unit patients with renal insufficiency. Aust Crit Care. 2022 05; 35(3):258-263.
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Brain insulin signaling and cerebrovascular disease in human postmortem brain. Acta Neuropathol Commun. 2021 04 15; 9(1):71.
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Abnormal food timing and predisposition to weight gain: Role of barrier dysfunction and microbiota. Transl Res. 2021 05; 231:113-123.
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Electronic Measurement of a Clinical Quality Measure for Inpatient Hypoglycemic Events: A Multicenter Validation Study. Med Care. 2020 10; 58(10):927-933.
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Evaluation and Management of the Critically Ill Adult With Diabetic Ketoacidosis. J Emerg Med. 2020 Sep; 59(3):371-383.
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Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function. Ann Neurol. 2020 09; 88(3):513-525.