"Tandem Mass Spectrometry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
| Descriptor ID |
D053719
|
| MeSH Number(s) |
E05.196.566.880
|
| Concept/Terms |
Tandem Mass Spectrometry- Tandem Mass Spectrometry
- Mass Spectrometry, Tandem
- Mass Spectrometry-Mass Spectrometry
- Mass Spectrometry Mass Spectrometry
|
Below are MeSH descriptors whose meaning is more general than "Tandem Mass Spectrometry".
Below are MeSH descriptors whose meaning is more specific than "Tandem Mass Spectrometry".
This graph shows the total number of publications written about "Tandem Mass Spectrometry" by people in this website by year, and whether "Tandem Mass Spectrometry" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tandem Mass Spectrometry" by people in Profiles.
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APOE e4 and Alzheimer's disease diagnosis associated differences in L-carnitine, GBB, TMAO, and acylcarnitines in blood and brain. Curr Res Transl Med. 2023 Jan-Mar; 71(1):103362.
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Characterizing the proteome of bullous pemphigoid blister fluid utilizing tandem mass tag labeling coupled with LC-MS/MS. Arch Dermatol Res. 2022 Nov; 314(9):921-928.
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Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss. J Proteome Res. 2021 05 07; 20(5):2266-2282.
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Proteomic Analysis and Cell Viability of Nine Amnion, Chorion, Umbilical Cord, and Amniotic Fluid-Derived Products. Cartilage. 2021 12; 13(2_suppl):495S-507S.
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Application of a glycinated bile acid biomarker for diagnosis and assessment of response to treatment in Niemann-pick disease type C1. Mol Genet Metab. 2020 12; 131(4):405-417.
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Application of N-palmitoyl-O-phosphocholineserine for diagnosis and assessment of response to treatment in Niemann-Pick type C disease. Mol Genet Metab. 2020 04; 129(4):292-302.
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Diagnosis of niemann-pick C1 by measurement of bile acid biomarkers in archived newborn dried blood spots. Mol Genet Metab. 2019 02; 126(2):183-187.
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Single-nephron proteomes connect morphology and function in proteinuric kidney disease. Kidney Int. 2018 06; 93(6):1308-1319.
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Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. BMC Gastroenterol. 2016 Feb 29; 16:30.
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Determination of hair ketamine cut-off value from Hong Kong ketamine users by LC-MS/MS analysis. Forensic Sci Int. 2016 Feb; 259:53-8.