Immunoglobulin Switch Region
"Immunoglobulin Switch Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.
| Descriptor ID |
D007134
|
| MeSH Number(s) |
G05.360.340.024.340.137.430 G05.360.340.024.340.335.300.500
|
| Concept/Terms |
Immunoglobulin Switch Region- Immunoglobulin Switch Region
- Ig Switch Sequences
- Ig Switch Sequence
- Sequence, Ig Switch
- Sequences, Ig Switch
- Switch Sequence, Ig
- Switch Sequences, Ig
- Switch Region, Immunoglobulin
- Immunoglobulin Switch Regions
- Region, Immunoglobulin Switch
- Regions, Immunoglobulin Switch
- Switch Regions, Immunoglobulin
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Switch Region".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Switch Region".
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Below are the most recent publications written about "Immunoglobulin Switch Region" by people in Profiles.
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Lineage and stage specificity of isotype switching in humans. J Immunol. 1988 Nov 15; 141(10):3625-33.