"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
| Descriptor ID |
D019210
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| MeSH Number(s) |
D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Troponin I".
Below are MeSH descriptors whose meaning is more specific than "Troponin I".
This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Troponin I" by people in Profiles.
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Accuracy of the European Society of Cardiology 0/1-, 0/2-, and 0/3-hour algorithms for diagnosing acute myocardial infarction. Acad Emerg Med. 2022 Apr; 29(4):512-514.
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Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts. J Stroke Cerebrovasc Dis. 2019 May; 28(5):1173-1177.
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The long-term prognostic value of highly sensitive cardiac troponin I in patients with acute pulmonary embolism. Clin Cardiol. 2017 Dec; 40(12):1271-1278.
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Circulating MicroRNAs as new biomarkers of ischaemia/reperfusion injury during cardiac surgery. Cardiology. 2015; 130(4):234-6.
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The prognostic value of undetectable highly sensitive cardiac troponin I in patients with acute pulmonary embolism. Chest. 2015 Mar; 147(3):685-694.
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Cardiac abnormalities in patients with acute subdural hemorrhage. Neurocrit Care. 2013 Oct; 19(2):176-82.
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Troponin elevation in subarachnoid hemorrhage does not impact in-hospital mortality. Neurocrit Care. 2013 Jun; 18(3):368-73.
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Evidence-based review and discussion points. Am J Crit Care. 2010 Nov; 19(6):530-1.
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Serum cardiac troponin T, but not troponin I, is elevated in idiopathic inflammatory myopathies. J Rheumatol. 2009 Dec; 36(12):2711-4.
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Cardiac troponin I and acute lung injury after subarachnoid hemorrhage. Neurocrit Care. 2009; 11(2):177-82.