"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
| Descriptor ID |
D001647
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| MeSH Number(s) |
D04.210.500.105
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".
Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".
This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.
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Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification. Sci Rep. 2021 09 23; 11(1):18964.
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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study. PLoS Med. 2021 05; 18(5):e1003615.
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Application of a glycinated bile acid biomarker for diagnosis and assessment of response to treatment in Niemann-pick disease type C1. Mol Genet Metab. 2020 12; 131(4):405-417.
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Shared Causal Paths underlying Alzheimer's dementia and Type 2 Diabetes. Sci Rep. 2020 03 05; 10(1):4107.
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Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. Alzheimers Dement. 2019 01; 15(1):76-92.
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Diagnosis of niemann-pick C1 by measurement of bile acid biomarkers in archived newborn dried blood spots. Mol Genet Metab. 2019 02; 126(2):183-187.
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Development of a bile acid-based newborn screen for Niemann-Pick disease type C. Sci Transl Med. 2016 05 04; 8(337):337ra63.
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Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring). 2009 Sep; 17(9):1671-7.
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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006 Jan 26; 439(7075):484-9.
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Differential induction of hepatic dysfunction after intraportal and intravenous challenge with endotoxin and Staphylococcal enterotoxin B. Shock. 2003 Apr; 19(4):352-7.