"Acetazolamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Descriptor ID |
D000086
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MeSH Number(s) |
D02.886.675.867.060 D03.383.129.708.867.060
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetazolamide".
Below are MeSH descriptors whose meaning is more specific than "Acetazolamide".
This graph shows the total number of publications written about "Acetazolamide" by people in this website by year, and whether "Acetazolamide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetazolamide" by people in Profiles.
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Adjunctive acetazolamide therapy for the treatment of Bartter syndrome. Int Urol Nephrol. 2020 Jan; 52(1):121-128.
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Spontaneous CSF leaks: factors predictive of additional interventions. Laryngoscope. 2010 Nov; 120(11):2141-6.
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Acetazolamide for prevention of contrast-induced nephropathy: a new use for an old drug. Pediatr Cardiol. 2006 Mar-Apr; 27(2):238-42.
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Therapy for status epilepticus. Clin Neuropharmacol. 1983; 6(4):255-69.