"Carboxypeptidase B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
Descriptor ID |
D025901
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MeSH Number(s) |
D08.811.277.656.350.245.125 D08.811.277.656.350.555.225 D08.811.277.656.675.555.225 D08.811.277.656.837.092
|
Concept/Terms |
Carboxypeptidase B2- Carboxypeptidase B2
- Arginine Carboxypeptidase
- Carboxypeptidase R
- Thrombin-Activatable Fibrinolysis Inhibitor
- Thrombin Activatable Fibrinolysis Inhibitor
- Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
- Carboxypeptidase B2, Plasma
- Plasma Carboxypeptidase B2
- Carboxypeptidase U
|
Below are MeSH descriptors whose meaning is more general than "Carboxypeptidase B2".
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