"Clarithromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
| Descriptor ID |
D017291
|
| MeSH Number(s) |
D02.540.576.500.992.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clarithromycin".
Below are MeSH descriptors whose meaning is more specific than "Clarithromycin".
This graph shows the total number of publications written about "Clarithromycin" by people in this website by year, and whether "Clarithromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clarithromycin" by people in Profiles.
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In vitro activity of macrolides against intracellular Legionella pneumophila. Diagn Microbiol Infect Dis. 1996 Jul; 25(3):123-6.
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Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. Antimicrob Agents Chemother. 1995 Dec; 39(12):2803-6.
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Comparative in vitro activity of A-56268 (TE-031) against gram-positive and gram-negative bacteria and Chlamydia trachomatis. Eur J Clin Microbiol. 1987 Apr; 6(2):173-8.
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In vitro activity of A-56268 (TE-031), a new macrolide, compared with that of erythromycin and clindamycin against selected gram-positive and gram-negative organisms. Antimicrob Agents Chemother. 1987 Feb; 31(2):328-30.
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In vitro activity of A-56268 (TE-031) and four other antimicrobial agents against Chlamydia trachomatis. Antimicrob Agents Chemother. 1987 Jan; 31(1):100-1.