"Drug Carriers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
| Descriptor ID |
D004337
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| MeSH Number(s) |
D26.255.260 E02.319.300.380
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Drug Carriers".
Below are MeSH descriptors whose meaning is more specific than "Drug Carriers".
This graph shows the total number of publications written about "Drug Carriers" by people in this website by year, and whether "Drug Carriers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Drug Carriers" by people in Profiles.
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Randomized study of danoprevir/ritonavir-based therapy for HCV genotype 1 patients with prior partial or null responses to peginterferon/ribavirin. J Hepatol. 2015 Feb; 62(2):294-302.
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Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 04; 31(46):5422-9.
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Nanoparticles for improved local retention after intra-articular injection into the knee joint. Pharm Res. 2013 Jan; 30(1):257-68.
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Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
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An evaluation of hepatotoxicity and nephrotoxicity of liposomal amphotericin B (L-AMB). J Med Toxicol. 2011 Mar; 7(1):12-5.
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Evaluation of early null response to pegylated interferon and ribavirin as a predictor of therapeutic nonresponse in patients undergoing treatment for chronic hepatitis C. Am J Gastroenterol. 2011 Mar; 106(3):452-8.
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Recombinant botulinum neurotoxin A heavy chain-based delivery vehicles for neuronal cell targeting. Protein Eng Des Sel. 2011 Mar; 24(3):247-53.
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Cloning and characterization of a single-chain fragment of monoclonal antibody to ACE suitable for lung endothelial targeting. Microvasc Res. 2010 Dec; 80(3):355-64.
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Characterization and performance of nucleic acid nanoparticles combined with protamine and gold. Biomaterials. 2009 Nov; 30(32):6451-9.
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Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair. Clin Orthop Relat Res. 1999 Apr; (361):216-27.