Depressive Disorder, Treatment-Resistant
"Depressive Disorder, Treatment-Resistant" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)
Descriptor ID |
D061218
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MeSH Number(s) |
F03.600.300.388
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Concept/Terms |
Depressive Disorder, Treatment-Resistant- Depressive Disorder, Treatment-Resistant
- Depressive Disorder, Treatment Resistant
- Depressive Disorders, Treatment-Resistant
- Disorder, Treatment-Resistant Depressive
- Disorders, Treatment-Resistant Depressive
- Treatment-Resistant Depressive Disorder
- Treatment-Resistant Depressive Disorders
- Refractory Depression
- Depression, Refractory
- Depressions, Refractory
- Refractory Depressions
- Therapy-Resistant Depression
- Depression, Therapy-Resistant
- Depressions, Therapy-Resistant
- Therapy Resistant Depression
- Therapy-Resistant Depressions
- Treatment Resistant Depression
- Depression, Treatment Resistant
- Depressions, Treatment Resistant
- Resistant Depression, Treatment
- Resistant Depressions, Treatment
- Treatment Resistant Depressions
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Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Treatment-Resistant".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Treatment-Resistant".
This graph shows the total number of publications written about "Depressive Disorder, Treatment-Resistant" by people in this website by year, and whether "Depressive Disorder, Treatment-Resistant" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Depressive Disorder, Treatment-Resistant" by people in Profiles.
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Safety and Tolerability of Concomitant Intranasal Esketamine Treatment With Irreversible, Nonselective MAOIs: A Case Series. J Clin Psychiatry. 2023 02 01; 84(2).
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Double-blind, placebo-controlled, proof-of-concept trial of a kappa-selective opioid receptor antagonist augmentation in treatment-resistant depression. Ann Clin Psychiatry. 2020 02; 32(4):18-26.
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Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial. JAMA Psychiatry. 2019 09 01; 76(9):893-903.
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A 5-Year Observational Study of Patients With Treatment-Resistant Depression Treated With Vagus Nerve Stimulation or Treatment as Usual: Comparison of Response, Remission, and Suicidality. Am J Psychiatry. 2017 07 01; 174(7):640-648.
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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study. Neuropsychopharmacology. 2017 Mar; 42(4):844-853.
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Can Medication Free, Treatment-Resistant, Depressed Patients Who Initially Respond to TMS Be Maintained Off Medications? A Prospective, 12-Month Multisite Randomized Pilot Study. Brain Stimul. 2016 Mar-Apr; 9(2):251-7.
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Effect of adjunctive L-methylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: results from a randomized clinical trial. J Clin Psychiatry. 2014 Aug; 75(8):855-63.
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The concept of "the will to thrive" in mental health. Issues Ment Health Nurs. 2012 Nov; 33(11):805-7.
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A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A Study). Psychother Psychosom. 2012; 81(2):87-97.