Receptors, Metabotropic Glutamate
"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.
| Descriptor ID |
D018094
|
| MeSH Number(s) |
D12.776.543.750.695.450 D12.776.543.750.720.200.450.500
|
| Concept/Terms |
Receptors, Metabotropic Glutamate- Receptors, Metabotropic Glutamate
- Metabotropic Glutamate Receptor
- Glutamate Receptor, Metabotropic
- Receptor, Metabotropic Glutamate
- Metabotropic Glutamate Receptors
- Receptors, Glutamate, Metabotropic
- Glutamate Receptors, Metabotropic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".
This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in this website by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.
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Cellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetamine. J Neurochem. 2013 Aug; 126(4):503-17.
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mGluR5 is necessary for maintenance of methamphetamine-induced associative learning. Eur Neuropsychopharmacol. 2013 Jul; 23(7):691-6.
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Fragile X syndrome and targeted treatment trials. Results Probl Cell Differ. 2012; 54:297-335.
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Reversal of fragile X phenotypes by manipulation of A?PP/A? levels in Fmr1KO mice. PLoS One. 2011; 6(10):e26549.
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Brain region-selective cellular redistribution of mGlu5 but not GABA(B) receptors following methamphetamine-induced associative learning. Synapse. 2011 Dec; 65(12):1333-43.
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Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond. Neuropsychopharmacology. 2012 Jan; 37(1):178-95.
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Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Sci Transl Med. 2011 Jan 05; 3(64):64ra1.
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A pilot open label, single dose trial of fenobam in adults with fragile X syndrome. J Med Genet. 2009 Apr; 46(4):266-71.
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Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome. J Dev Behav Pediatr. 2008 Aug; 29(4):293-302.