"Genes, BRCA2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)
| Descriptor ID |
D024522
|
| MeSH Number(s) |
G05.360.340.024.340.375.249.105 G05.360.340.024.340.415.400.105
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Genes, BRCA2".
Below are MeSH descriptors whose meaning is more specific than "Genes, BRCA2".
This graph shows the total number of publications written about "Genes, BRCA2" by people in this website by year, and whether "Genes, BRCA2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, BRCA2" by people in Profiles.
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Paired tumor sequencing and germline testing in breast cancer management: An experience of a single academic center. Cancer Rep (Hoboken). 2020 12; 3(6):e1287.
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Hereditary diffuse gastric cancer and lynch syndromes in a BRCA1/2 negative breast cancer patient. Breast Cancer Res Treat. 2017 Nov; 166(1):315-319.
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Living With Genetic Vulnerability: a Life Course Perspective. J Genet Couns. 2016 Feb; 25(1):49-61.
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The Supremes got it right. Am J Ther. 2013 Jul-Aug; 20(4):315.
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Theory development from studies with young women with breast cancer who are BRCA mutation negative. ANS Adv Nurs Sci. 2013 Apr-Jun; 36(2):E41-53.
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Being young, female, and BRCA positive. Am J Nurs. 2012 Oct; 112(10):26-31, quiz 46, 32.
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Hereditary inflammatory breast cancer associated with BRCA2 mutation: a rare disease presentation in mother and daughter. Clin Adv Hematol Oncol. 2012 Jun; 10(6):402-4.
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Conditions and consequences of a BRCA mutation in young, single women of childbearing age. Oncol Nurs Forum. 2010 Sep; 37(5):627-34.
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Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry. JAMA. 2005 Oct 19; 294(15):1925-33.