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Connection

Michael Fill to Calcium

This is a "connection" page, showing publications Michael Fill has written about Calcium.
Connection Strength

6.010
  1. Simulating cardiac Ca2+ release units: effects of RyR cluster size and Ca2+ buffers on diastolic Ca2+ leak. Pflugers Arch. 2021 03; 473(3):435-446.
    View in: PubMed
    Score: 0.547
  2. Approaching ryanodine receptor therapeutics from the calcin angle. J Gen Physiol. 2016 05; 147(5):369-73.
    View in: PubMed
    Score: 0.392
  3. Sarcoplasmic reticulum K(+) (TRIC) channel does not carry essential countercurrent during Ca(2+) release. Biophys J. 2013 Sep 03; 105(5):1151-60.
    View in: PubMed
    Score: 0.326
  4. Pernicious attrition and inter-RyR2 CICR current control in cardiac muscle. J Mol Cell Cardiol. 2013 May; 58:53-8.
    View in: PubMed
    Score: 0.313
  5. Is ryanodine receptor a calcium or magnesium channel? Roles of K+ and Mg2+ during Ca2+ release. Cell Calcium. 2012 Jun; 51(6):427-33.
    View in: PubMed
    Score: 0.294
  6. Flux regulation of cardiac ryanodine receptor channels. J Gen Physiol. 2010 Jan; 135(1):15-27.
    View in: PubMed
    Score: 0.252
  7. Ryanodine receptor luminal Ca2+ regulation: swapping calsequestrin and channel isoforms. Biophys J. 2009 Oct 07; 97(7):1961-70.
    View in: PubMed
    Score: 0.249
  8. Luminal Ca2+ regulation of single cardiac ryanodine receptors: insights provided by calsequestrin and its mutants. J Gen Physiol. 2008 Apr; 131(4):325-34.
    View in: PubMed
    Score: 0.223
  9. Disrupting the feed-forward cycle of RyR1 Ca2+ leak and oxidative stress mitigates doxorubicin-induced skeletal myopathy. Am J Physiol Cell Physiol. 2026 07 01; 331(1):C59-C73.
    View in: PubMed
    Score: 0.197
  10. Age-Dependent Effects of Muscle Resting Calcium on Fasting Blood Glucose: Implications for Prediabetes Risk. Endocrinol Diabetes Metab. 2025 05; 8(3):e70052.
    View in: PubMed
    Score: 0.183
  11. Calcium regulation of single cardiac ryanodine receptor channels. J Muscle Res Cell Motil. 2004; 25(8):603-4.
    View in: PubMed
    Score: 0.167
  12. Ryanodine receptor calcium release channels. Physiol Rev. 2002 Oct; 82(4):893-922.
    View in: PubMed
    Score: 0.153
  13. Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.
    View in: PubMed
    Score: 0.122
  14. Ryanodine receptor permeation and gating: glowing cinders that underlie the Ca2+ spark. J Gen Physiol. 1999 Jul; 114(1):159-61.
    View in: PubMed
    Score: 0.122
  15. Ryanodine Receptor Open Times Are Determined in the Closed State. Biophys J. 2018 10 02; 115(7):1160-1165.
    View in: PubMed
    Score: 0.115
  16. Coordinated feet and the dance of ryanodine receptors. Science. 1998 Aug 07; 281(5378):790-1.
    View in: PubMed
    Score: 0.115
  17. Sarcoplasmic Reticulum Ca2+ Release Uses a?Cascading Network of Intra-SR and Channel Countercurrents. Biophys J. 2018 01 23; 114(2):462-473.
    View in: PubMed
    Score: 0.110
  18. Adaptation of single cardiac ryanodine receptor channels. Biophys J. 1997 Feb; 72(2 Pt 1):691-7.
    View in: PubMed
    Score: 0.103
  19. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. J Biol Chem. 2017 01 27; 292(4):1385-1395.
    View in: PubMed
    Score: 0.102
  20. Sarcoplasmic reticulum Ca2+, Mg2+, K+, and Cl- concentrations adjust quickly as heart rate changes. J Mol Cell Cardiol. 2017 02; 103:31-39.
    View in: PubMed
    Score: 0.102
  21. Nebivolol suppresses cardiac ryanodine receptor-mediated spontaneous Ca2+ release and catecholaminergic polymorphic ventricular tachycardia. Biochem J. 2016 Nov 15; 473(22):4159-4172.
    View in: PubMed
    Score: 0.100
  22. Non-?-blocking R-carvedilol enantiomer suppresses Ca2+ waves and stress-induced ventricular tachyarrhythmia without lowering heart rate or blood pressure. Biochem J. 2015 Sep 01; 470(2):233-42.
    View in: PubMed
    Score: 0.093
  23. Cytosolic Ca?? buffering determines the intra-SR Ca?? concentration at which cardiac Ca?? sparks terminate. Cell Calcium. 2015 Sep; 58(3):246-53.
    View in: PubMed
    Score: 0.092
  24. The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice. Biochem J. 2014 Jul 01; 461(1):99-106.
    View in: PubMed
    Score: 0.086
  25. Activation of single cardiac and skeletal ryanodine receptor channels by flash photolysis of caged Ca2+. Biophys J. 1994 Jun; 66(6):1879-86.
    View in: PubMed
    Score: 0.086
  26. The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias. Nat Med. 2014 Feb; 20(2):184-92.
    View in: PubMed
    Score: 0.084
  27. Ryanodine receptor adaptation: control mechanism of Ca(2+)-induced Ca2+ release in heart. Science. 1993 May 07; 260(5109):807-9.
    View in: PubMed
    Score: 0.080
  28. Abnormal termination of Ca2+ release is a common defect of RyR2 mutations associated with cardiomyopathies. Circ Res. 2012 Mar 30; 110(7):968-77.
    View in: PubMed
    Score: 0.073
  29. Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med. 2011 Jul 10; 17(8):1003-9.
    View in: PubMed
    Score: 0.070
  30. Effect of perchlorate on calcium release in skinned fibres stimulated by ionic substitution and caffeine. Pflugers Arch. 1990 Mar; 415(6):688-92.
    View in: PubMed
    Score: 0.064
  31. Abnormal ryanodine receptor channels in malignant hyperthermia. Biophys J. 1990 Mar; 57(3):471-5.
    View in: PubMed
    Score: 0.064
  32. Reinterpreting the anomalous mole fraction effect: the ryanodine receptor case study. Biophys J. 2009 Oct 21; 97(8):2212-21.
    View in: PubMed
    Score: 0.062
  33. Ca2+ entry-independent effects of L-type Ca2+ channel modulators on Ca2+ sparks in ventricular myocytes. Am J Physiol Cell Physiol. 2007 Jun; 292(6):C2129-40.
    View in: PubMed
    Score: 0.052
  34. Calcium release rate in skinned skeletal muscle fibers measured with arsenazo III. Am J Physiol. 1986 Feb; 250(2 Pt 1):C245-55.
    View in: PubMed
    Score: 0.048
  35. Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. Circulation. 2025 Mar 25; 151(12):847-862.
    View in: PubMed
    Score: 0.044
  36. Alda-1 attenuation of binge alcohol-caused atrial arrhythmias through a novel mechanism of suppressed c-Jun N-terminal Kinase-2 activity. J Mol Cell Cardiol. 2024 12; 197:11-19.
    View in: PubMed
    Score: 0.044
  37. Differential Ca2+ and Sr2+ regulation of intracellular divalent cations release in ventricular myocytes. Cell Calcium. 2004 Aug; 36(2):119-34.
    View in: PubMed
    Score: 0.043
  38. Calcium regulation of single ryanodine receptor channel gating analyzed using HMM/MCMC statistical methods. J Gen Physiol. 2004 May; 123(5):533-53.
    View in: PubMed
    Score: 0.043
  39. Single channel function of inositol 1,4,5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras. J Gen Physiol. 2003 May; 121(5):399-411.
    View in: PubMed
    Score: 0.040
  40. Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation. Pflugers Arch. 2023 05; 475(5):569-581.
    View in: PubMed
    Score: 0.039
  41. Mechanisms that turn-off intracellular calcium release channels. Front Biosci. 2003 Jan 01; 8:d46-54.
    View in: PubMed
    Score: 0.039
  42. A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice. J Cell Physiol. 2022 08; 237(8):3305-3316.
    View in: PubMed
    Score: 0.037
  43. Differential activation by Ca2+, ATP and caffeine of cardiac and skeletal muscle ryanodine receptors after block by Mg2+. J Membr Biol. 2002 May 01; 187(1):51-64.
    View in: PubMed
    Score: 0.037
  44. Cardiac ryanodine receptor calcium release deficiency syndrome. Sci Transl Med. 2021 02 03; 13(579).
    View in: PubMed
    Score: 0.034
  45. Sarcoplasmic reticulum calcium release is stimulated and inhibited by daunorubicin and daunorubicinol. Toxicol Appl Pharmacol. 2000 Dec 01; 169(2):168-76.
    View in: PubMed
    Score: 0.034
  46. Ryanodine receptor adaptation. J Gen Physiol. 2000 Dec; 116(6):873-82.
    View in: PubMed
    Score: 0.034
  47. Spatial Ca(2+) distribution in contracting skeletal and cardiac muscle cells. Biophys J. 2000 Jan; 78(1):164-73.
    View in: PubMed
    Score: 0.032
  48. Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects. Circ Res. 1998 Dec 14-28; 83(12):1192-204.
    View in: PubMed
    Score: 0.029
  49. Kinetic properties of DM-nitrophen and calcium indicators: rapid transient response to flash photolysis. Pflugers Arch. 1997 Sep; 434(5):615-31.
    View in: PubMed
    Score: 0.027
  50. Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity. J Gen Physiol. 2017 Feb; 149(2):199-218.
    View in: PubMed
    Score: 0.026
  51. Models of Ca2+ release channel adaptation. Science. 1995 Mar 31; 267(5206):2009-10.
    View in: PubMed
    Score: 0.023
  52. Surface charge potentiates conduction through the cardiac ryanodine receptor channel. J Gen Physiol. 1994 May; 103(5):853-67.
    View in: PubMed
    Score: 0.021
  53. Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions. J Gen Physiol. 2013 Aug; 142(2):127-36.
    View in: PubMed
    Score: 0.020
  54. Cytoplasmic Ca2+ does not inhibit the cardiac muscle sarcoplasmic reticulum ryanodine receptor Ca2+ channel, although Ca(2+)-induced Ca2+ inactivation of Ca2+ release is observed in native vesicles. J Membr Biol. 1993 Jul; 135(1):49-59.
    View in: PubMed
    Score: 0.020
  55. Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10312-7.
    View in: PubMed
    Score: 0.020
  56. Antibodies as probes for ligand gating of single sarcoplasmic reticulum Ca2(+)-release channels. Biochem J. 1991 Jan 15; 273(Pt 2):449-57.
    View in: PubMed
    Score: 0.017
  57. Contractile activation and recovery in skinned frog muscle stimulated by ionic substitution. Am J Physiol. 1988 Jan; 254(1 Pt 1):C107-14.
    View in: PubMed
    Score: 0.014
  58. Ryanodine receptor function in newborn rat heart. Am J Physiol Heart Circ Physiol. 2005 May; 288(5):H2527-40.
    View in: PubMed
    Score: 0.011
  59. Pulsed local-field fluorescence microscopy: a new approach for measuring cellular signals in the beating heart. Pflugers Arch. 2003 Mar; 445(6):747-58.
    View in: PubMed
    Score: 0.010
  60. Gating kinetics and ligand sensitivity modified by phosphorylation of cardiac ryanodine receptors. Pflugers Arch. 2002 May; 444(1-2):202-12.
    View in: PubMed
    Score: 0.009
  61. Single-channel function of recombinant type 2 inositol 1,4, 5-trisphosphate receptor. Biophys J. 2000 Sep; 79(3):1388-99.
    View in: PubMed
    Score: 0.008
  62. Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels. Biophys J. 1998 Aug; 75(2):834-9.
    View in: PubMed
    Score: 0.007
  63. Functionally heterogenous ryanodine receptors in avian cerebellum. J Biol Chem. 1996 Jul 19; 271(29):17028-34.
    View in: PubMed
    Score: 0.006
  64. Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum. J Gen Physiol. 1988 Jul; 92(1):1-26.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.