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Antonio Bianco to Iodide Peroxidase

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This is a "connection" page, showing publications Antonio Bianco has written about Iodide Peroxidase.
Antonio Bianco
Connection Strength
22.285
Iodide Peroxidase
  1. Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 05 01; 163(5).
    View in: PubMed
    Score: 0.720
  2. Deiodinases and the Metabolic Code for Thyroid Hormone Action. Endocrinology. 2021 08 01; 162(8).
    View in: PubMed
    Score: 0.683
  3. Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis. Alcohol Clin Exp Res. 2019 07; 43(7):1376-1383.
    View in: PubMed
    Score: 0.584
  4. Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain. J Clin Invest. 2019 01 02; 129(1):230-245.
    View in: PubMed
    Score: 0.568
  5. Pathophysiological relevance of deiodinase polymorphism. Curr Opin Endocrinol Diabetes Obes. 2018 10; 25(5):341-346.
    View in: PubMed
    Score: 0.561
  6. A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans. J Clin Endocrinol Metab. 2018 05 01; 103(5):1818-1826.
    View in: PubMed
    Score: 0.545
  7. The Deiodinase Trio and Thyroid Hormone Signaling. Methods Mol Biol. 2018; 1801:67-83.
    View in: PubMed
    Score: 0.533
  8. Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):14018-23.
    View in: PubMed
    Score: 0.458
  9. Coupling between Nutrient Availability and Thyroid Hormone Activation. J Biol Chem. 2015 Dec 18; 290(51):30551-61.
    View in: PubMed
    Score: 0.458
  10. Scope and limitations of iodothyronine deiodinases in hypothyroidism. Nat Rev Endocrinol. 2015 Nov; 11(11):642-652.
    View in: PubMed
    Score: 0.456
  11. Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes. Endocrinology. 2015 Oct; 156(10):3842-52.
    View in: PubMed
    Score: 0.450
  12. Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes. J Clin Endocrinol Metab. 2015 Mar; 100(3):920-33.
    View in: PubMed
    Score: 0.434
  13. Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine. J Clin Invest. 2015 Feb; 125(2):769-81.
    View in: PubMed
    Score: 0.433
  14. Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic ?-cells and disrupts glucose homeostasis. Endocrinology. 2014 Aug; 155(8):3160-71.
    View in: PubMed
    Score: 0.416
  15. Tissue-specific inactivation of type 2 deiodinase reveals multilevel control of fatty acid oxidation by thyroid hormone in the mouse. Diabetes. 2014 May; 63(5):1594-604.
    View in: PubMed
    Score: 0.406
  16. The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex. Mol Endocrinol. 2013 Dec; 27(12):2105-15.
    View in: PubMed
    Score: 0.400
  17. Coordination of hypothalamic and pituitary T3 production regulates TSH expression. J Clin Invest. 2013 Apr; 123(4):1492-500.
    View in: PubMed
    Score: 0.383
  18. Cracking the code for thyroid hormone signaling. Trans Am Clin Climatol Assoc. 2013; 124:26-35.
    View in: PubMed
    Score: 0.377
  19. Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling. Biochim Biophys Acta. 2013 Jul; 1830(7):3956-64.
    View in: PubMed
    Score: 0.368
  20. Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism. J Neurosci. 2012 Jun 20; 32(25):8491-500.
    View in: PubMed
    Score: 0.363
  21. Absence of myocardial thyroid hormone inactivating deiodinase results in restrictive cardiomyopathy in mice. Mol Endocrinol. 2012 May; 26(5):809-18.
    View in: PubMed
    Score: 0.356
  22. Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis. Mol Endocrinol. 2011 Dec; 25(12):2065-75.
    View in: PubMed
    Score: 0.348
  23. The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion. Endocrinology. 2011 Oct; 152(10):3717-27.
    View in: PubMed
    Score: 0.342
  24. Type 2 deiodinase at the crossroads of thyroid hormone action. Int J Biochem Cell Biol. 2011 Oct; 43(10):1432-41.
    View in: PubMed
    Score: 0.338
  25. Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes. 2011 Apr; 60(4):1082-9.
    View in: PubMed
    Score: 0.331
  26. The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure. FEBS Lett. 2011 Feb 04; 585(3):539-44.
    View in: PubMed
    Score: 0.329
  27. Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment. Endocrinology. 2010 Dec; 151(12):5961-70.
    View in: PubMed
    Score: 0.323
  28. Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep; 151(9):4573-82.
    View in: PubMed
    Score: 0.318
  29. Covering the base-pairs in iodothyronine deiodinase-1 biology: holes remain in the lineup. Thyroid. 2009 Oct; 19(10):1027-9.
    View in: PubMed
    Score: 0.301
  30. The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. Mol Cell Biol. 2009 Oct; 29(19):5339-47.
    View in: PubMed
    Score: 0.298
  31. Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev. 2008 Dec; 29(7):898-938.
    View in: PubMed
    Score: 0.280
  32. The thyroid hormone-inactivating deiodinase functions as a homodimer. Mol Endocrinol. 2008 Jun; 22(6):1382-93.
    View in: PubMed
    Score: 0.271
  33. Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences. Cell Mol Life Sci. 2008 Feb; 65(4):570-90.
    View in: PubMed
    Score: 0.268
  34. Reawakened interest in type III iodothyronine deiodinase in critical illness and injury. Nat Clin Pract Endocrinol Metab. 2008 Mar; 4(3):148-55.
    View in: PubMed
    Score: 0.268
  35. An inside job. Endocrinology. 2007 Jul; 148(7):3077-9.
    View in: PubMed
    Score: 0.257
  36. Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity. Mol Cell Biol. 2007 Jul; 27(13):4774-83.
    View in: PubMed
    Score: 0.254
  37. Deiodinases: implications of the local control of thyroid hormone action. J Clin Invest. 2006 Oct; 116(10):2571-9.
    View in: PubMed
    Score: 0.244
  38. Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism. Endocrinology. 2006 Apr; 147(4):1735-43.
    View in: PubMed
    Score: 0.232
  39. Cellular and structural biology of the deiodinases. Thyroid. 2005 Aug; 15(8):777-86.
    View in: PubMed
    Score: 0.225
  40. Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse. Endocrinology. 2005 Mar; 146(3):1568-75.
    View in: PubMed
    Score: 0.216
  41. Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation. Endocrinology. 2005 Jan; 146(1):195-200.
    View in: PubMed
    Score: 0.213
  42. Triplets! Unexpected structural similarity among the three enzymes that catalyze initiation and termination of thyroid hormone effects. Arq Bras Endocrinol Metabol. 2004 Feb; 48(1):16-24.
    View in: PubMed
    Score: 0.208
  43. Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis. Diabetes. 2004 Mar; 53(3):577-84.
    View in: PubMed
    Score: 0.204
  44. Localized T3 production modifies the transcriptome and promotes the hepatocyte-like lineage in iPSC-derived hepatic organoids. JCI Insight. 2023 Dec 08; 8(23).
    View in: PubMed
    Score: 0.201
  45. Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2. Mol Endocrinol. 2003 Dec; 17(12):2603-12.
    View in: PubMed
    Score: 0.197
  46. The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure. J Biol Chem. 2003 Sep 19; 278(38):36887-96.
    View in: PubMed
    Score: 0.195
  47. Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation. J Clin Invest. 2003 Jul; 112(2):189-96.
    View in: PubMed
    Score: 0.195
  48. In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases. Endocrinology. 2003 Mar; 144(3):937-46.
    View in: PubMed
    Score: 0.191
  49. Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. J Biol Chem. 2003 Jan 10; 278(2):1206-11.
    View in: PubMed
    Score: 0.186
  50. Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase. Mol Endocrinol. 2002 Sep; 16(9):1999-2007.
    View in: PubMed
    Score: 0.184
  51. Heterozygote Advantage of the Type II Deiodinase Thr92Ala Polymorphism on Intrahospital Mortality of COVID-19. J Clin Endocrinol Metab. 2022 05 17; 107(6):e2488-e2501.
    View in: PubMed
    Score: 0.180
  52. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb; 23(1):38-89.
    View in: PubMed
    Score: 0.177
  53. The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest. 2001 Nov; 108(9):1379-85.
    View in: PubMed
    Score: 0.174
  54. Deiodinase-3 is a thyrostat to regulate podocyte homeostasis. EBioMedicine. 2021 Oct; 72:103617.
    View in: PubMed
    Score: 0.173
  55. Neonatal thyroxine activation modifies epigenetic programming of the liver. Nat Commun. 2021 07 21; 12(1):4446.
    View in: PubMed
    Score: 0.170
  56. The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line. J Biol Chem. 2001 Aug 10; 276(32):30183-7.
    View in: PubMed
    Score: 0.170
  57. Assessment of children in the autistic spectrum disorder that carry the Thr92Ala-DIO2 polymorphism. J Endocrinol Invest. 2021 Aug; 44(8):1775-1782.
    View in: PubMed
    Score: 0.165
  58. Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation. Mol Endocrinol. 2000 Nov; 14(11):1697-708.
    View in: PubMed
    Score: 0.162
  59. Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy. Endocrinology. 2000 Nov; 141(11):4309-12.
    View in: PubMed
    Score: 0.162
  60. Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism. Thyroid. 2021 02; 31(2):202-207.
    View in: PubMed
    Score: 0.161
  61. Paradigms of Dynamic Control of Thyroid Hormone Signaling. Endocr Rev. 2019 08 01; 40(4):1000-1047.
    View in: PubMed
    Score: 0.149
  62. Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice. Endocrinology. 2018 08 01; 159(8):3090-3104.
    View in: PubMed
    Score: 0.139
  63. Thyroxine 5'-deiodination mediates norepinephrine-induced lipogenesis in dispersed brown adipocytes. Endocrinology. 1998 Feb; 139(2):571-8.
    View in: PubMed
    Score: 0.134
  64. Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function. Thyroid. 2017 04; 27(4):577-586.
    View in: PubMed
    Score: 0.125
  65. Thyroid hormone activation by type?2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-? coactivator-1a expression in skeletal muscle. J Physiol. 2016 09 15; 594(18):5255-69.
    View in: PubMed
    Score: 0.121
  66. Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice. Endocrinology. 2016 09; 157(9):3682-95.
    View in: PubMed
    Score: 0.121
  67. New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism. Lancet Diabetes Endocrinol. 2015 Oct; 3(10):756-8.
    View in: PubMed
    Score: 0.114
  68. Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. Chem Res Toxicol. 2015 Jun 15; 28(6):1265-74.
    View in: PubMed
    Score: 0.111
  69. Defending plasma T3 is a biological priority. Clin Endocrinol (Oxf). 2014 Nov; 81(5):633-41.
    View in: PubMed
    Score: 0.105
  70. The role of thyroid hormone and brown adipose tissue in energy homoeostasis. Lancet Diabetes Endocrinol. 2013 Nov; 1(3):250-8.
    View in: PubMed
    Score: 0.100
  71. Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice. Endocrinology. 2013 Oct; 154(10):3937-46.
    View in: PubMed
    Score: 0.098
  72. Minireview: cracking the metabolic code for thyroid hormone signaling. Endocrinology. 2011 Sep; 152(9):3306-11.
    View in: PubMed
    Score: 0.085
  73. Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells. J Clin Invest. 2010 Jun; 120(6):2206-17.
    View in: PubMed
    Score: 0.078
  74. Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway. J Endocrinol. 2010 May; 205(2):179-86.
    View in: PubMed
    Score: 0.077
  75. Triumphs of the thyroid despite lesser conversion. Endocrinology. 2009 Jun; 150(6):2502-4.
    View in: PubMed
    Score: 0.073
  76. For some, L-thyroxine replacement might not be enough: a genetic rationale. J Clin Endocrinol Metab. 2009 May; 94(5):1521-3.
    View in: PubMed
    Score: 0.073
  77. Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes. Endocrinology. 2009 Apr; 150(4):1976-83.
    View in: PubMed
    Score: 0.071
  78. Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton. Bone. 2008 Nov; 43(5):921-30.
    View in: PubMed
    Score: 0.069
  79. Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats. J Clin Invest. 2008 Mar; 118(3):975-83.
    View in: PubMed
    Score: 0.067
  80. Metabolic effects of thyroid hormones-beyond traditional prospects. Thyroid. 2008 Feb; 18(2):99-100.
    View in: PubMed
    Score: 0.067
  81. Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14466-71.
    View in: PubMed
    Score: 0.065
  82. Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain. Endocrinology. 2007 Oct; 148(10):4865-74.
    View in: PubMed
    Score: 0.064
  83. Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study. Endocrinology. 2007 Oct; 148(10):4786-92.
    View in: PubMed
    Score: 0.064
  84. Type 2 iodothyronine deiodinase is highly expressed in germ cells of adult rat testis. J Endocrinol. 2007 Jul; 194(1):47-54.
    View in: PubMed
    Score: 0.064
  85. The role of glucocorticoids in the stress-induced reduction of extrathyroidal 3,5,3'-triiodothyronine generation in rats. Endocrinology. 1987 Mar; 120(3):1033-8.
    View in: PubMed
    Score: 0.063
  86. The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation. Diabetes. 2007 Mar; 56(3):767-76.
    View in: PubMed
    Score: 0.063
  87. Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations. Endocrinology. 2007 Mar; 148(3):954-60.
    View in: PubMed
    Score: 0.062
  88. Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization. J Biol Chem. 2006 Oct 20; 281(42):31538-43.
    View in: PubMed
    Score: 0.061
  89. Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene. Endocrinology. 2006 Sep; 147(9):4419-29.
    View in: PubMed
    Score: 0.060
  90. Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels. Brain Res. 2005 Sep 14; 1056(1):97-9.
    View in: PubMed
    Score: 0.057
  91. The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol. 2005 Jul; 7(7):698-705.
    View in: PubMed
    Score: 0.056
  92. Adaptive activation of thyroid hormone and energy expenditure. Biosci Rep. 2005 Jun-Aug; 25(3-4):191-208.
    View in: PubMed
    Score: 0.056
  93. The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2005 Jun; 90(6):3472-8.
    View in: PubMed
    Score: 0.055
  94. Chronic cardiac-specific thyrotoxicosis increases myocardial beta-adrenergic responsiveness. Mol Endocrinol. 2004 Jul; 18(7):1840-9.
    View in: PubMed
    Score: 0.052
  95. Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome. Endocrinology. 2004 Apr; 145(4):1649-55.
    View in: PubMed
    Score: 0.050
  96. Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase. JCO Precis Oncol. 2022 06; 6:e2100496.
    View in: PubMed
    Score: 0.045
  97. Regional physiological adaptation of the central nervous system deiodinases to iodine deficiency. Am J Physiol Endocrinol Metab. 2001 Jul; 281(1):E54-61.
    View in: PubMed
    Score: 0.042
  98. Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467.
    View in: PubMed
    Score: 0.041
  99. Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center. Endocrinology. 2000 Mar; 141(3):1127-35.
    View in: PubMed
    Score: 0.039
  100. 3,5,3'-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity. Am J Physiol. 1999 01; 276(1):E179-87.
    View in: PubMed
    Score: 0.036
  101. A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action. Endocrinology. 2018 02 01; 159(2):1159-1171.
    View in: PubMed
    Score: 0.034
  102. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function. Nat Med. 2018 01; 24(1):39-49.
    View in: PubMed
    Score: 0.033
  103. Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold. Endocrinology. 1991 Apr; 128(4):2149-59.
    View in: PubMed
    Score: 0.021
  104. Thyroid hormone-related regulation of gene expression in human fatty liver. J Clin Endocrinol Metab. 2009 Sep; 94(9):3521-9.
    View in: PubMed
    Score: 0.018
  105. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006 Jan 26; 439(7075):484-9.
    View in: PubMed
    Score: 0.015
  106. Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis. Endocrinology. 2006 Mar; 147(3):1438-51.
    View in: PubMed
    Score: 0.014
  107. Quantitation of brown adipose tissue perfusion in transgenic mice using near-infrared fluorescence imaging. Mol Imaging. 2003 01; 2(1):37-49.
    View in: PubMed
    Score: 0.012
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The connection strength for concepts is the sum of the scores for each matching publication.

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