David Williams to Humans
This is a "connection" page, showing publications David Williams has written about Humans.
Connection Strength
0.530
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Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties. J Immunol. 2018 01 15; 200(2):788-799.
Score: 0.034
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The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004279.
Score: 0.030
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Cellular and molecular mechanisms of fungal ?-(1?6)-glucan in macrophages. Innate Immun. 2015 Oct; 21(7):759-69.
Score: 0.029
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Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast. J Biol Chem. 2014 Feb 07; 289(6):3432-43.
Score: 0.026
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Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites. Antioxid Redox Signal. 2013 Sep 01; 19(7):735-45.
Score: 0.024
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The redox biology of schistosome parasites and applications for drug development. Curr Pharm Des. 2012; 18(24):3595-611.
Score: 0.023
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Thioredoxin glutathione reductase: its role in redox biology and potential as a target for drugs against neglected diseases. Biochim Biophys Acta. 2011 Dec; 1810(12):1262-71.
Score: 0.022
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Characterization of the methionine sulfoxide reductases of Schistosoma mansoni. J Parasitol. 2009 Dec; 95(6):1421-8.
Score: 0.020
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Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nat Med. 2008 Apr; 14(4):407-12.
Score: 0.017
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Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching. J Pharmacol Exp Ther. 2008 Apr; 325(1):115-23.
Score: 0.017
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Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni. J Biol Chem. 2004 Jun 18; 279(25):26159-66.
Score: 0.013
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Characterisation of a Rho homologue of Schistosoma mansoni. Int J Parasitol. 2003 Jul; 33(7):721-31.
Score: 0.013
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Glycogen Metabolism in Candida albicans Impacts Fitness and Virulence during Vulvovaginal and Invasive Candidiasis. mBio. 2023 04 25; 14(2):e0004623.
Score: 0.012
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Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways. JCI Insight. 2023 01 10; 8(1).
Score: 0.012
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Human monocyte scavenger receptors are pattern recognition receptors for (1-->3)-beta-D-glucans. J Leukoc Biol. 2002 Jul; 72(1):140-6.
Score: 0.012
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Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol. 2022 05; 51:102278.
Score: 0.011
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Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 02 15; 208(4):785-792.
Score: 0.011
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Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function. NPJ Biofilms Microbiomes. 2021 12 08; 7(1):87.
Score: 0.011
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Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections. Molecules. 2020 Nov 01; 25(21).
Score: 0.010
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Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris. Nat Microbiol. 2020 12; 5(12):1516-1531.
Score: 0.010
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Engineering Nanogels for Drug Delivery to Pathogenic Fungi Aspergillus fumigatus by Tuning Polymer Amphiphilicity. Biomacromolecules. 2020 08 10; 21(8):3112-3121.
Score: 0.010
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Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med. 2020 02 01; 147:200-211.
Score: 0.010
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Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics. PLoS One. 2019; 14(6):e0217019.
Score: 0.009
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Candida albicans ?-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages. Front Immunol. 2018; 9:2818.
Score: 0.009
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Mannan Molecular Substructures Control Nanoscale Glucan Exposure in Candida. Cell Rep. 2018 08 28; 24(9):2432-2442.e5.
Score: 0.009
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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem Biol. 2018 08 17; 13(8):2190-2202.
Score: 0.009
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Impaired phagocytosis directs human monocyte activation in response to fungal derived ?-glucan particles. Eur J Immunol. 2018 05; 48(5):757-770.
Score: 0.009
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High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis. Infect Dis Poverty. 2015 Aug 31; 4:40.
Score: 0.007
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Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J. 2015 Aug; 282(16):3199-217.
Score: 0.007
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Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats. Antioxid Redox Signal. 2015 May 20; 22(15):1337-51.
Score: 0.007
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Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003534.
Score: 0.007
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An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Cytokine. 2015 Feb; 71(2):215-22.
Score: 0.007
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Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation. ACS Chem Biol. 2014 Mar 21; 9(3):821-30.
Score: 0.007
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Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A. Chem Biol. 2013 Aug 22; 20(8):991-1001.
Score: 0.006
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The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans. PLoS Pathog. 2013; 9(4):e1003276.
Score: 0.006
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Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway. J Immunol. 2013 Apr 15; 190(8):4129-35.
Score: 0.006
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Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents. Org Biomol Chem. 2012 Aug 21; 10(31):6375-87.
Score: 0.006
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Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni. PLoS Negl Trop Dis. 2012; 6(6):e1686.
Score: 0.006
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Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. J Med Chem. 2009 Oct 22; 52(20):6474-83.
Score: 0.005
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The macrophage mannose receptor induces IL-17 in response to Candida albicans. Cell Host Microbe. 2009 Apr 23; 5(4):329-40.
Score: 0.005
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Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem. 2008 Jul 18; 283(29):20590-9.
Score: 0.004
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Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol. 2008 Feb; 38(2):500-6.
Score: 0.004
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Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl Trop Dis. 2008 Jan 02; 2(1):e127.
Score: 0.004
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Soluble Dectin-1 as a tool to detect beta-glucans. J Immunol Methods. 2006 Jul 31; 314(1-2):164-9.
Score: 0.004
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Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest. 2006 Jun; 116(6):1642-50.
Score: 0.004
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Differential production in vitro of antigen specific IgG1, IgG3 and IgA: a study in Schistosoma haematobium infected individuals. Parasite Immunol. 2003 Jan; 25(1):39-44.
Score: 0.003