David Williams to Schistosoma mansoni
This is a "connection" page, showing publications David Williams has written about Schistosoma mansoni.
Connection Strength
2.611
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Synthesis of Methoxylated Benzoxanthones as Drug Metabolites of Antischistosomal Schistodiones-A Limited Environmental Risk. Molecules. 2026 May 27; 31(11).
Score: 0.240
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Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets. J Biol Chem. 2006 Jun 23; 281(25):17001-17010.
Score: 0.237
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Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni. J Med Chem. 2026 Apr 23; 69(8):9242-9264.
Score: 0.236
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The "Doorstop Pocket" In Thioredoxin Reductases-An Unexpected Druggable Regulator of the Catalytic Machinery. J Med Chem. 2024 Sep 26; 67(18):15947-15967.
Score: 0.213
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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. ACS Infect Dis. 2021 07 09; 7(7):1932-1944.
Score: 0.169
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Molecular and enzymatic characterization of Schistosoma mansoni thioredoxin peroxidase. J Parasitol. 2000 Oct; 86(5):908-15.
Score: 0.162
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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem Biol. 2018 08 17; 13(8):2190-2202.
Score: 0.138
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Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J. 2015 Aug; 282(16):3199-217.
Score: 0.113
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New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni. Eur J Med Chem. 2014 Sep 12; 84:135-45.
Score: 0.105
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Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents. Org Biomol Chem. 2012 Aug 21; 10(31):6375-6387.
Score: 0.092
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Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni. PLoS Negl Trop Dis. 2012; 6(6):e1686.
Score: 0.091
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Molecular cloning and sequencing of glutathione peroxidase from Schistosoma mansoni. Mol Biochem Parasitol. 1992 May; 52(1):127-30.
Score: 0.090
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Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Structure. 2012 Mar 07; 20(3):429-39.
Score: 0.089
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Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16; 284(42):28977-85.
Score: 0.075
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The genome of the blood fluke Schistosoma mansoni. Nature. 2009 Jul 16; 460(7253):352-8.
Score: 0.074
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Biomphalaria glabrata peroxiredoxin: effect of schistosoma mansoni infection on differential gene regulation. Mol Biochem Parasitol. 2009 Sep; 167(1):20-31.
Score: 0.073
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Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J. 2008 Nov; 22(11):4022-32.
Score: 0.070
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A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase. Assay Drug Dev Technol. 2008 Aug; 6(4):551-5.
Score: 0.070
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Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl Trop Dis. 2008 Jan 02; 2(1):e127.
Score: 0.067
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Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni. J Virol. 2003 Jun; 77(11):6153-66.
Score: 0.049
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Traditional Kenyan herbal medicine: exploring natural products' therapeutics against schistosomiasis. J Helminthol. 2022 Mar 03; 96:e16.
Score: 0.045
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Construction and characterization of a Schistosoma mansoni bacterial artificial chromosome library. Genomics. 2000 Apr 15; 65(2):87-94.
Score: 0.039
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Schistosoma mansoni: characterization of sequence variants of the 28-kDa glutathione S-transferase. Exp Parasitol. 1994 Aug; 79(1):81-4.
Score: 0.026
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Cloning and characterization of the gene encoding Schistosoma mansoni glutathione peroxidase. Gene. 1994 Jan 28; 138(1-2):149-52.
Score: 0.025
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On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases. J Inorg Biochem. 2012 Mar; 108:105-11.
Score: 0.022