David Williams to Multienzyme Complexes
This is a "connection" page, showing publications David Williams has written about Multienzyme Complexes.
Connection Strength
1.236
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Thioredoxin glutathione reductase: its role in redox biology and potential as a target for drugs against neglected diseases. Biochim Biophys Acta. 2011 Dec; 1810(12):1262-71.
Score: 0.344
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Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med. 2020 02 01; 147:200-211.
Score: 0.154
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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem Biol. 2018 08 17; 13(8):2190-2202.
Score: 0.139
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Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J. 2015 Aug; 282(16):3199-217.
Score: 0.114
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Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation. ACS Chem Biol. 2014 Mar 21; 9(3):821-30.
Score: 0.102
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On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases. J Inorg Biochem. 2012 Mar; 108:105-11.
Score: 0.088
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Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16; 284(42):28977-85.
Score: 0.076
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Examination of Coligands in Mefloquine-Metal Complexes Reveals the Structural Determinants of Activity against Plasmodium falciparum and Schistosoma mansoni. J Med Chem. 2026 Apr 23; 69(8):9242-9264.
Score: 0.059
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The "Doorstop Pocket" In Thioredoxin Reductases-An Unexpected Druggable Regulator of the Catalytic Machinery. J Med Chem. 2024 Sep 26; 67(18):15947-15967.
Score: 0.054
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Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. ACS Infect Dis. 2021 07 09; 7(7):1932-1944.
Score: 0.042
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New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni. Eur J Med Chem. 2014 Sep 12; 84:135-45.
Score: 0.026
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Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. J Med Chem. 2009 Oct 22; 52(20):6474-83.
Score: 0.019
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Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade. PLoS Negl Trop Dis. 2008 Jan 02; 2(1):e127.
Score: 0.017