Myasthenia Gravis, Autoimmune, Experimental
"Myasthenia Gravis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
Descriptor ID |
D020720
|
MeSH Number(s) |
C10.114.656.300 C10.114.703.350 C10.668.758.725.300 C20.111.258.500.300 C20.111.258.625.350 E05.598.500.500.750
|
Concept/Terms |
Myasthenia Gravis, Autoimmune, Experimental- Myasthenia Gravis, Autoimmune, Experimental
- Myasthenia Gravis, Experimental Autoimmune
- Experimental Myasthenia Gravis
- Myasthenia Gravis, Experimental
- Autoimmune Experimental Myasthenia Gravis
- Experimental Myasthenia
- Experimental Myasthenias
- Myasthenia, Experimental
- Myasthenias, Experimental
- Myasthenia Gravis, Autoimmune Experimental
|
Below are MeSH descriptors whose meaning is more general than "Myasthenia Gravis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Myasthenia Gravis [C10.114.656]
- Myasthenia Gravis, Autoimmune, Experimental [C10.114.656.300]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Myasthenia Gravis, Autoimmune, Experimental [C10.114.703.350]
- Neuromuscular Diseases [C10.668]
- Neuromuscular Junction Diseases [C10.668.758]
- Myasthenia Gravis [C10.668.758.725]
- Myasthenia Gravis, Autoimmune, Experimental [C10.668.758.725.300]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Myasthenia Gravis [C20.111.258.500]
- Myasthenia Gravis, Autoimmune, Experimental [C20.111.258.500.300]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Myasthenia Gravis, Autoimmune, Experimental [C20.111.258.625.350]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Myasthenia Gravis, Autoimmune, Experimental [E05.598.500.500.750]
Below are MeSH descriptors whose meaning is more specific than "Myasthenia Gravis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Myasthenia Gravis, Autoimmune, Experimental" by people in this website by year, and whether "Myasthenia Gravis, Autoimmune, Experimental" was a major or minor topic of these publications.
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Below are the most recent publications written about "Myasthenia Gravis, Autoimmune, Experimental" by people in Profiles.
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Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis. J Autoimmun. 2014 Aug; 52:64-73.
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GM-CSF-induced regulatory T cells selectively inhibit anti-acetylcholine receptor-specific immune responses in experimental myasthenia gravis. J Neuroimmunol. 2011 Dec 15; 240-241:65-73.
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Acetylcholine receptor-alpha subunit expression in myasthenia gravis: a role for the autoantigen in pathogenesis? Muscle Nerve. 2009 Aug; 40(2):279-86.
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Regulatory T cells induced by GM-CSF suppress ongoing experimental myasthenia gravis. Clin Immunol. 2008 Aug; 128(2):172-80.
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Strategies for treating autoimmunity: novel insights from experimental myasthenia gravis. Ann N Y Acad Sci. 2008; 1132:276-82.
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Suppression of experimental autoimmune myasthenia gravis by granulocyte-macrophage colony-stimulating factor is associated with an expansion of FoxP3+ regulatory T cells. J Immunol. 2006 Oct 15; 177(8):5296-306.
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Predictive value of serum anti-C1q antibody levels in experimental autoimmune myasthenia gravis. Neuromuscul Disord. 2006 Feb; 16(2):137-43.