"Complement C4b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
| Descriptor ID |
D015935
|
| MeSH Number(s) |
D12.776.124.486.274.350.260
|
| Concept/Terms |
Complement C4b- Complement C4b
- C4b, Complement
- Complement 4b
- Complement Component 4b
- Component 4b, Complement
- C4b Complement
- Complement, C4b
|
Below are MeSH descriptors whose meaning is more general than "Complement C4b".
Below are MeSH descriptors whose meaning is more specific than "Complement C4b".
This graph shows the total number of publications written about "Complement C4b" by people in this website by year, and whether "Complement C4b" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement C4b" by people in Profiles.
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Acute Cellular Rejection and C4d Positivity in Heart Transplantation : A Manifestation of Asymptomatic Antibody-Mediated Rejection? Am J Clin Pathol. 2016 Feb; 145(2):238-43.
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The value of C4d deposit in post liver transplant liver biopsies. Transpl Immunol. 2012 Dec; 27(4):166-70.
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C4d-positive acute antibody-mediated rejection due to anti-HLA-DP antibody: a tale of one patient and a review of the University of Wisconsin experience. Clin Transpl. 2006; 503-7.
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Elevated levels of iC3b and C4d, but not Bb, complement fragments from plasma of persons infected with human T cell leukemia virus (HTLV) with HTLV-I-associated myelopathy/tropical spastic paraparesis. J Infect Dis. 1995 Oct; 172(4):1095-7.
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Decreased levels of complement receptor 1 (CD35) on B lymphocytes in persons with HIV infection. Clin Immunol Immunopathol. 1995 Apr; 75(1):20-5.