"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
| Descriptor ID |
D001973
|
| MeSH Number(s) |
D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
|
| Concept/Terms |
Bromodeoxyuridine- Bromodeoxyuridine
- Bromouracil Deoxyriboside
- Deoxyriboside, Bromouracil
- 5-Bromo-2'-deoxyuridine
- 5 Bromo 2' deoxyuridine
- BrdU
- BUdR
- 5-Bromodeoxyuridine
- 5 Bromodeoxyuridine
- Broxuridine
|
Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".
Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".
This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.
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Long-term, homologous prolactin, administered through ectopic pituitary grafts, induces hypothalamic dopamine neuron differentiation in adult Snell dwarf mice. Endocrinology. 2008 Apr; 149(4):2010-8.
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Focal cerebral ischemia induces changes in both MMP-13 and aggrecan around individual neurons. Brain Res. 2005 Sep 14; 1056(1):43-50.
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Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nat Immunol. 2005 Aug; 6(8):793-9.
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RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus. J Neurosci Methods. 2005 Jun 15; 144(2):197-201.
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Differential expression of vascular endothelial growth factor-A (VEGF-A) and VEGF-B after brain injury. J Neuropathol Exp Neurol. 2002 Sep; 61(9):778-88.
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Cell cycle kinetic studies in 68 patients with myelodysplastic syndromes following intravenous iodo- and/or bromodeoxyuridine. Exp Hematol. 1997 Jun; 25(6):530-5.
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In vivo labelling with halogenated pyrimidines of squamous cell carcinomas and adjacent non-involved mucosa of head and neck region. Cell Prolif. 1995 Sep; 28(9):497-509.
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Cell kinetics of head and neck cancers. Clin Cancer Res. 1995 May; 1(5):527-37.
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Relationship of [3H]Ara-C incorporation and response to therapy with high-dose Ara-C in AML patients: a Leukemia Intergroup study. Exp Hematol. 1992 Nov; 20(10):1194-200.
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Detection of BrdU in the regenerating bone marrow cells of a patient with AML. Leuk Res. 1989; 13(12):1055-9.