"Rifampin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
| Descriptor ID |
D012293
|
| MeSH Number(s) |
D03.633.400.811.700 D04.345.295.750.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rifampin".
Below are MeSH descriptors whose meaning is more specific than "Rifampin".
This graph shows the total number of publications written about "Rifampin" by people in this website by year, and whether "Rifampin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Rifampin" by people in Profiles.
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Strategies for preventing catheter-related bloodstream infections: the role of new technologies. Crit Care Med. 2006 Mar; 34(3):905-7.
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Osteoarticular tuberculosis: current diagnosis and treatment. Am J Ther. 2000 Nov; 7(6):393-8.
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Impact of rifampin on serum amiodarone concentrations in a patient with congenital heart disease. Pharmacotherapy. 1999 Feb; 19(2):249-51.
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Successful treatment of acquired immunodeficiency syndrome-related Mycobacterium avium complex disease with a multiple drug regimen including amikacin. Arch Intern Med. 1991 Mar; 151(3):582-5.
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In vitro activity of minocycline and rifampin against staphylococci. Diagn Microbiol Infect Dis. 1989 May-Jun; 12(3):253-5.