"CD4 Immunoadhesins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
| Descriptor ID |
D016860
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| MeSH Number(s) |
D12.644.541.500.697.249 D12.776.124.486.485.538.500.249 D12.776.124.486.485.680.697.249 D12.776.124.790.651.538.500.249 D12.776.124.790.651.680.660.249 D12.776.377.715.548.538.500.249 D12.776.377.715.548.680.660.249 D12.776.395.550.200.230 D12.776.543.550.200.230 D12.776.828.300.200 D23.050.301.350.230
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "CD4 Immunoadhesins".
Below are MeSH descriptors whose meaning is more specific than "CD4 Immunoadhesins".
This graph shows the total number of publications written about "CD4 Immunoadhesins" by people in this website by year, and whether "CD4 Immunoadhesins" was a major or minor topic of these publications.
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Below are the most recent publications written about "CD4 Immunoadhesins" by people in Profiles.
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HIV-1 strain dependence of complement-mediated virolysis induced by recombinant CD4-IgG. J Acquir Immune Defic Syndr (1988). 1994 Jan; 7(1):100-1.