"Photobleaching" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Light-induced change in a chromophore, resulting in the loss of its absorption of light of a particular wave length. The photon energy causes a conformational change in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS in the CELL MEMBRANE.
| Descriptor ID |
D038761
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| MeSH Number(s) |
G02.740.680
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Photobleaching".
Below are MeSH descriptors whose meaning is more specific than "Photobleaching".
This graph shows the total number of publications written about "Photobleaching" by people in this website by year, and whether "Photobleaching" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photobleaching" by people in Profiles.
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A novel method for spatially complex diffraction-limited photoactivation and photobleaching in living cells. J Physiol. 2012 Mar 01; 590(5):1093-100.
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Lipid peroxides promote large rafts: effects of excitation of probes in fluorescence microscopy and electrochemical reactions during vesicle formation. Biophys J. 2006 Sep 15; 91(6):2172-83.