1-Methyl-3-isobutylxanthine
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"1-Methyl-3-isobutylxanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
    
			
			
				
				
					
						| Descriptor ID | 
										
							D015056
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						| MeSH Number(s) | 
						
							 D03.633.100.759.758.824.751.500 
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						| Concept/Terms | 
						
							1-Methyl-3-isobutylxanthine- 1-Methyl-3-isobutylxanthine
 - 1 Methyl 3 isobutylxanthine
 - IBMX
 - Isobutyltheophylline
 - 3-Isobutyl-1-methylxanthine
 - 3 Isobutyl 1 methylxanthine
 
  
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				Below are MeSH descriptors whose meaning is more general than "1-Methyl-3-isobutylxanthine".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "1-Methyl-3-isobutylxanthine".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "1-Methyl-3-isobutylxanthine" by people in this website by year, and whether "1-Methyl-3-isobutylxanthine" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1997 | 0 | 1 | 1 | 
| 2004 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "1-Methyl-3-isobutylxanthine" by people in Profiles.
						
					
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Chronic hypoxic decreases in soluble guanylate cyclase protein and enzyme activity are age dependent in fetal and adult ovine carotid arteries. J Appl Physiol (1985). 2006 Jun; 100(6):1857-66.
															
								 
							
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Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels. J Biol Chem. 2004 Dec 10; 279(50):52095-105.
															
								 
							
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Effect of recombinant interleukin-6 and thrombopoietin on isolated guinea pig bone marrow megakaryocyte protein phosphorylation and proplatelet formation. Blood Cells Mol Dis. 1997 Aug; 23(2):252-68.
															
								 
							
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Platelet serotonin studies in hyperserotonemic relatives of children with autistic disorder. Life Sci. 1993; 52(25):2005-15.
															
								 
							
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Cyclic AMP metabolism in fragile X syndrome. Ann Neurol. 1992 Jan; 31(1):22-6.
															
								 
							
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Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20). J Neurochem. 1988 Apr; 50(4):1287-96.
															
								 
							
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Work in progress: radioprotection of human breast cancer cells by elevation of intracellular cyclic AMP. Radiology. 1983 Jul; 148(1):289-90.