"ERG1 Potassium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
| Descriptor ID |
D000072237
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.249.500 D12.776.543.550.450.750.900.249.500 D12.776.543.585.400.750.900.249.500
|
| Concept/Terms |
ERG1 Potassium Channel- ERG1 Potassium Channel
- Channel, ERG1 Potassium
- Potassium Channel, ERG1
- Potassium Voltage-Gated Channel, Subfamily H, Member 2
- Ether-A-Go-Go-Related Potassium Channel 1
- Ether A Go Go Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel- Kv11.1 Protein-Potassium Channel
- Channel, Kv11.1 Protein-Potassium
- Kv11.1 Protein Potassium Channel
- Protein-Potassium Channel, Kv11.1
|
Below are MeSH descriptors whose meaning is more general than "ERG1 Potassium Channel".
Below are MeSH descriptors whose meaning is more specific than "ERG1 Potassium Channel".
This graph shows the total number of publications written about "ERG1 Potassium Channel" by people in this website by year, and whether "ERG1 Potassium Channel" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "ERG1 Potassium Channel" by people in Profiles.
-
The effects of chiral isolates of methadone on the cardiac potassium channel IKr. Cardiology. 2009; 113(1):59-65.
-
Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide. Cardiology. 2008; 110(3):209-16.
-
The additive effects of the active component of grapefruit juice (naringenin) and antiarrhythmic drugs on HERG inhibition. Cardiology. 2008; 110(3):145-52.
-
A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels. Am J Ther. 2005 Jul-Aug; 12(4):328-36.
-
Idiosyncratic gating of HERG-like K+ channels in microglia. J Gen Physiol. 1998 Jun; 111(6):795-805.
-
HERG-like K+ channels in microglia. J Gen Physiol. 1998 Jun; 111(6):781-94.