"Uncoupling Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial uncoupling protein that is expressed in BROWN ADIPOSE TISSUE. It is critical for NONSHIVERING THERMOGENESIS to prevent heat loss in NEONATES.
| Descriptor ID |
D000071256
|
| MeSH Number(s) |
D12.776.157.530.937.598.500 D12.776.543.585.475.688.500 D12.776.543.585.937.696.500 D12.776.575.750.688.500
|
| Concept/Terms |
Uncoupling Protein 1- Uncoupling Protein 1
- BAT Uncoupling Protein
- Uncoupling Protein, BAT
- Thermogenin
- UCP1 Protein
- Uncoupling Protein, Mitochondrial Membrane
- Mitochondrial Brown Fat Uncoupling Protein 1
- Solute Carrier Family 25 Member 7
- SLC25A7 Protein
- Brown Adipose Tissue Uncoupling Protein
- Mitochondrial Uncoupling Protein
- Uncoupling Protein, Mitochondrial
|
Below are MeSH descriptors whose meaning is more general than "Uncoupling Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Uncoupling Protein 1".
This graph shows the total number of publications written about "Uncoupling Protein 1" by people in this website by year, and whether "Uncoupling Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Uncoupling Protein 1" by people in Profiles.
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Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 05 01; 163(5).
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Inactivation of the adrenergic receptor ?2 disrupts glucose homeostasis in mice. J Endocrinol. 2014 Jun; 221(3):381-90.
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The role of thyroid hormone and brown adipose tissue in energy homoeostasis. Lancet Diabetes Endocrinol. 2013 Nov; 1(3):250-8.
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Dexamethasone reduces energy expenditure and increases susceptibility to diet-induced obesity in mice. Obesity (Silver Spring). 2013 Sep; 21(9):E415-20.
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?(1) Adrenergic receptor is key to cold- and diet-induced thermogenesis in mice. J Endocrinol. 2012 Sep; 214(3):359-65.
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Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40.
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Mice lacking brain-type creatine kinase activity show defective thermoregulation. Physiol Behav. 2009 Apr 20; 97(1):76-86.
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Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue. J Lipid Res. 2007 Jun; 48(6):1273-9.
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Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis. Diabetes. 2004 Mar; 53(3):577-84.
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Quantitation of brown adipose tissue perfusion in transgenic mice using near-infrared fluorescence imaging. Mol Imaging. 2003 01; 2(1):37-49.